Antibiotics

For PV, as for other surgical procedures that implant devices into the body, intravenous antibiotics are routinely given (usually 30 minutes) before the procedure is begun. The most common antibiotic used in this application is cefazolin (1 g).46 If an alternative must be used because of allergy, ciprofloxacin (500 mg orally, two times daily) may be substituted and continued for 24 hours after the completion of the procedure. Optimally, an oral antibiotic should be started 12 hours before a PV procedure.

As mentioned earlier, antibiotics are added to the cement itself only in the situation of immunocompromise.

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Essentials of Human Physiology

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