• Paronychia is the most commonly seen infection of the hand
• Warm soaks and antibiotics effective if there is no drainage or fluctuance
• Eponychial marsupialization for chronic paronychia; also remove nail if signs of involvement
Herpetic whitlow Acute paronychia Chronic paronychia
This patient's presentation is typical of acute paronychia, an infection of the soft tissue folds surrounding the fingernail. The clinical presentation initially consists of localized tenderness of the paronychial region, with subsequent erythema,
Figure 5—2. Acute paro nychia, with characteristic erythema and swelling.
Figure 5—2. Acute paro nychia, with characteristic erythema and swelling.
swelling, and fluctuance (Fig. 5—2). Frank drainage and elevation of the nail plate are also seen.
Acute paronychia are often seen in nail biters, as well as after manicures or ingrown nails. The etiology of such infection is a break in the soft tissue seal on the dorsal periphery of the nail, allowing entry, colonization, and abscess formation by the offending organism. The infection begins in the lateral (paronychial) nail fold, and may spread to include the proximal nail fold (eponychium). In severe cases, the lesion may reach the contralateral paronychia, and is termed a runaround or horseshoe infection. Since a paronychia is essentially an infected abscess, definitive treatment typically requires surgical drainage. Typically, Staphylococcus aureus is the involved organism.
Chronic paronychia are persistent, indurated infections of the eponychium, and present somewhat differently from acute paronychia. It is typically seen in people whose hands are chronically exposed to water with detergents and alkali, such as cleaning workers, bartenders, and kitchen staff. The etiology is thought to include an initial bacterial infection, typically followed by superinfection and colonization of the eponychium with a fungus such as Candida albicans. There is subsequent episodic inflammation and drainage, as well as a fibrosis and thickening of the eponychium secondary to the chronic low-grade inflammatory response. The patient presents with less severe erythema and fluctuance than acute paronychia, and typically does not report as much localized tenderness. A typical sign of chronic paronychia is the appearance of longitudinal grooves on the dorsal surface of the nail plate, secondary to the long-term damage to the germinal tissues in the eponychium.
Both acute and chronic paronychia have been noted with an increased incidence in diabetics, immunocompromised patients, and those receiving anti-retroviral therapy.
The most important entity to distinguish from paronychia in the differential diagnosis is herpetic whitlow, a self-limited viral infection of the fingertips caused by the herpes simplex virus. It is transmitted by skin-to-skin contact, and is often seen in medical and dental personnel, as well as in children. As with paronychia, herpetic whitlow may also present with swelling and erythema, though typically patients have disproportionately greater pain than in the case of bacterial infections. Vesicles are also seen, containing fluid that may be clear or turbid, but is never purulent. The diagnosis is usually made clinically, though it is possible to confirm it by use of a Tzanck prep or viral culture. It is important to distinguish herpetic whitlow from bacterial infections, as a surgical incision for the former can lead to complications involving the entire digit or systemic spread, and is contraindicated.
Nonsurgical treatment of an acute paronychia should be attempted only in the earliest stage, where the infection has not progressed to more than a mild localized erythema and swelling. In such cases, a regimen consisting of an oral antibiotic with Staphylococcus coverage (e.g., dicloxacillin 250 to 500 mg po q6h), along with warm saline soaks and rest, may be adequate. Typically, however, by the time the patient presents to a physician, there is already abscess formation and fluctuance requiring drainage.
Conservative treatment of chronic paronychia by use of topical or systemic antibiotic and antifungal agents has almost universally been unsuccessful. It is thought that the process of fibrosis and chronic injury in the eponychium leads to a diminished vascular supply and decreased delivery of such drugs.
As previously stated, herpetic whitlow should generally be treated conservatively and typically runs a self-limited course of ~21 days. A notable exception is when bacterial superinfection is seen along with an abscess. In such cases the abscess may be carefully drained, with systemic acyclovir administered to reduce the likelihood of complications.
The goal of surgical intervention for a paronychia is to allow a thorough drainage of the purulent collection. At the same time, however, it is imperative that invasion of the nail bed be kept to a minimum to avoid future growth deformities. All of the procedures described may typically be performed under a digital block anesthesia.
In cases where there is only involvement of one of the lateral nail folds, a true skin incision is not necessary. A No. 11 or No. 15 blade is used to completely lift the paronychium from the nail plate, opening the abscess in the nail fold and allowing drainage. Care must be taken to direct the sharp edge of the scalpel toward the paronychial fold and away from the nail bed, to avoid an injury to the nail matrix that may result in scarring or growth deformities. If there is any involvement of the nail bed, it is best also to remove the affected side of the nail plate, using a Freer elevator to gently separate the lateral third of the nail from the nail bed, and then using a small pair of scissors to make a longitudinal cut and remove the nail plate.
When there is involvement of the eponychium and proximal nail in addition to the lateral fold, a single incision is made beginning at the midpoint of the paronychial fold and proceeding proximally through the eponychium to reach
the base of the nail. The soft tissues are elevated, and the proximal third of the nail is bluntly separated and excised with scissors (Fig. 5—3). In severe cases where a runaround or horseshoe infection involves both sides of the finger, a similar incision is made on the opposite side as well, and the entire eponychium is elevated.
Chronic paronychia are treated somewhat differently. Keyser and Eaton describe a technique of eponychial marsupialization that has been highly effective at clearing the persistent infection. A crescent of tissue ~ 1 mm proximal to the eponychial fold and 5 mm in width at its largest point is removed along with its subcutaneous tissue, taking care to not penetrate so deep as to encroach on the germinal nail matrix (Fig. 5—4). Bendar and Lane subsequently reported success by removing only the superficial soft tissue, and excising the nail plate in cases where it was involved. We agree that the latter approach provides adequate treatment while minimizing unnecessary trauma to the nail bed.
In all of the above cases, the wound is thoroughly irrigated and packed with plain gauze or a nonadherent dressing. An oral antibiotic regimen is begun, and the dressing is kept on for 48 to 72 hours, at which point warm saline soaks are regularly performed until the irritation subsides.
Figure 5—4. Eponychial marsupialization for treatment ofchronic paronychia.
Abrams RA, Botte MJ. Hand infections: treatment recommendations for specific types. J Am Acad Orthop Surg 1996;4:219-230.
Bendar MS, Lane LB. Eponychial marsupialization and nail removal for surgical treatment of chronic paronychia. J Hand Surg 1991;16A:314-317.
Hurst LC, Gluck R. Herpetic whitlow with bacterial abscess. J Hand Surg 1991; 16A:311-314.
Jebson PJL. Infections of the fingertip. Hand Clin 1998;14:547-555.
Keyser JJ, Eaton EG. Surgical cure of chronic paronychia by eponychial marsupialization. Plast Reconstr Surg 1976;58:66-70.
Louis DS, Jebson PJL. Mimickers of hand infections. Hand Clin 1998;14:519-530.
Neviaser RJ. Infections. In: Green DP, ed. Operative Hand Surgery. 3rd ed. New York: Churchill Livingstone; 1993:1033-1036.
Polayers IM, Arons MS. The treatment of herpetic whitlow—a new surgical concept. Plast Reconstr Surg 1980;65:811-817.
Russo F, Collantes C, Guerrero J. Severe paronychia due to zidovudine-induced neutropenia in a neonate. J Am Acad Dermatol 1999;40:322-324.
Tosti A, Piraccini BM, D'Antuono A, Marzaduri S, Bettoli V. Paronychia associated with antiretroviral therapy. Br J Dermatol 1999;140:1165-1168.
Was this article helpful?
Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.