Rivkees and Crawford (5) published a meta-analysis of 30 studies that examined gonadal function after various chemotherapy regimens, which included 116 men who had been treated with cyclophosphamide alone. Gonadal function and/or histology were assessed by several different methods; semen analysis, basal LH and follicle-stimulating hormone (FSH) levels, and testicular biopsy were the most commonly used. Of the 116

patients, 52 (45%) had evidence of testicular dysfunction after treatment. The finding of gonadal dysfunction correlated with the total dose of cyclophosphamide, occurring in more than 80% of postpubertal patients who received more than 300 mg/kg.

Eliminating Stress and Anxiety From Your Life

Eliminating Stress and Anxiety From Your Life

It seems like you hear it all the time from nearly every one you know I'm SO stressed out!? Pressures abound in this world today. Those pressures cause stress and anxiety, and often we are ill-equipped to deal with those stressors that trigger anxiety and other feelings that can make us sick. Literally, sick.

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