1) The filtration coefficient is unusually high in the glomeruli. Compared with most other capillaries, the glomerular capillaries behave as though they had more pores per unit surface area; consequently, they have an unusually high hydraulic conductivity. The total glomerular filtration barrier area is large, about 2 m2.
2) Capillary hydrostatic pressure is higher in the glomeruli than in any other capillaries.
In summary, glomerular filtration is high because the glomerular capillary blood is exposed to a large porous surface and there is a high transmural pressure gradient.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.