Mitochondria Are Important for Synaptic Transmission

Mitochondria in neurons are highly concentrated in the region of the axon terminals. They produce ATP, which is required as a source of energy for many cellular processes. In the axon terminal, mitochondria provide both a source of energy for processes associated with synaptic transmission

Nucleus

Sornas

Retrograde transport

Axon<

Axon terminal

Pinocytosis uptake

Nucleus

Retrograde transport

Anterograde Retrograde Transmission

Golgi apparatus

Anterograde transport

Storage pool

Synaptic vesicles

Release

Anterograde and retrograde axoplasmic transport. Transport of molecules in vesicles along microtubules is mediated by kinesin for anterograde transport and by dynein for retrograde transport.

Rough ER

Golgi apparatus

Vesicle pool

Neurofilament Microtubule

Anterograde transport

Storage pool

Synaptic vesicles

Release

Anterograde and retrograde axoplasmic transport. Transport of molecules in vesicles along microtubules is mediated by kinesin for anterograde transport and by dynein for retrograde transport.

and substrates for the synthesis of certain neurotransmitter chemicals, such as the amino acid glutamate. In addition, mitochondria contain enzymes for degrading neurotransmitter molecules, such as MAO, which degrades catecholamines and 5-HT, and GABA-transaminase, which degrades GABA.

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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