Kidney Autoregulatory Range

Autoregulation Renal Artery

80 120 160 200 Mean arterial blood pressure (mm Hg)

Renal autoregulation, based on measurements in isolated, denervated, and perfused kidneys. In the autoregulatory range, renal blood flow and GFR stay relatively constant despite changes in arterial blood pressure. This is accomplished by changes in the resistance (caliber) of pre-glomerular blood vessels. The circles indicate that vessel radius (r) is smaller when blood pressure is high and larger when blood pressure is low. Since resistance to blood flow varies as r4, changes in vessel caliber are greatly exaggerated in this figure.

80 120 160 200 Mean arterial blood pressure (mm Hg)

Renal autoregulation, based on measurements in isolated, denervated, and perfused kidneys. In the autoregulatory range, renal blood flow and GFR stay relatively constant despite changes in arterial blood pressure. This is accomplished by changes in the resistance (caliber) of pre-glomerular blood vessels. The circles indicate that vessel radius (r) is smaller when blood pressure is high and larger when blood pressure is low. Since resistance to blood flow varies as r4, changes in vessel caliber are greatly exaggerated in this figure.

Gfr Autoregulation Macula Densa Feedback

The tubuloglomerular feedback mecha-'nism. When single nephron GFR is increased—for example, as a result of an increase in arterial blood pressure—more NaCl is delivered to and reabsorbed by the macula densa, leading to constriction of the nearby afferent arteriole. This negative-feedback system plays a role in renal blood flow and GFR autoregulation.

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Responses

  • shirley
    What is tobulo gelomeral fidback in kidney?
    7 years ago

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