How Kidneys Balance Blood Ph

Digestion

Respiratory Buffer System

JBpBHHIHil^ The maintenance of normal blood pH by ^tammU^mm^ chemical buffers, the respiratory system, and the kidneys. On a mixed diet, pH is threatened by the production of strong acids (sulfuric, hydrochloric, and phosphoric) mainly as a result of protein metabolism. These strong acids are buffered in the body by chemical buffer bases, such as ECF HCO 3 . The kidneys eliminate hydrogen ions (combined with urinary buffers) and anions in the urine. At the same time, they add new HCO3~ to the ECF, to replace the HCO3~ consumed in buffering strong acids. The respiratory system disposes of CO2.

JBpBHHIHil^ The maintenance of normal blood pH by ^tammU^mm^ chemical buffers, the respiratory system, and the kidneys. On a mixed diet, pH is threatened by the production of strong acids (sulfuric, hydrochloric, and phosphoric) mainly as a result of protein metabolism. These strong acids are buffered in the body by chemical buffer bases, such as ECF HCO 3 . The kidneys eliminate hydrogen ions (combined with urinary buffers) and anions in the urine. At the same time, they add new HCO3~ to the ECF, to replace the HCO3~ consumed in buffering strong acids. The respiratory system disposes of CO2.

mizes a change in pH but does not remove acid or base from the body.

2) Respiratory response. The respiratory system is the second line of defense of blood pH. Normally, breathing removes CO2 as fast as it forms. Large loads of acid stimulate breathing (respiratory compensation), which removes CO2 from the body and lowers the [H2CO3] in arterial blood, reducing the acidic shift in blood pH.

3) Renal response. The kidneys are the third line of defense of blood pH. Although chemical buffers in the body can bind H+ and the lungs can change [H2CO3] of blood, the burden of removing excess H+ falls directly on the kidneys. Hydrogen ions are excreted in combination with urinary buffers. At the same time, the kidneys add new HCO3~ to the ECF to replace HCO3~ used to buffer strong acids. The kidneys also excrete the anions (phosphate, chloride, sulfate) that are liberated from strong acids. The kidneys affect blood pH more slowly than other buffering mechanisms in the body,- full renal compensation may take 1 to 3 days.

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  • MARGARET
    How kidneys balance blood pH?
    7 years ago
  • starr galloway
    How kidneys and liver balance blood ph?
    4 years ago

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