The differential processing of prohormones. In alpha cells of the pancreas (left), the major bioactive product formed from proglucagon is glucagon itself. It is not currently known whether the other peptides are processed to produce biologically active molecules. In intestinal cells (right), proglucagon is cleaved to produce the four peptides shown. Glicentin is the major glucagon-containing peptide in the intestine. IP-1, intervening peptide 1, IP-2, intervening peptide 2, GLP-1, glucagon-like peptide-1, GLP-2, glucagon-like peptide 2.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.