Cardiopulmonary baroreceptors are located in the cardiac atria, at the junction of the great veins and atria, in the ven tricular myocardium, and in pulmonary vessels. Their nerve fibers run in the vagus nerve to the NTS, with projections to supramedullary areas as well. Unloading (i.e., decreasing the stretch) of the cardiopulmonary receptors by reducing central blood volume results in increased sympathetic nerve activity and decreased parasympathetic nerve activity to the heart and blood vessels. In addition, the car-diopulmonary reflex interacts with the baroreceptor reflex. Unloading of the cardiopulmonary receptors enhances the baroreceptor reflex, and loading the cardiopulmonary receptors, by increasing central blood volume, inhibits the baroreceptor reflex.
Was this article helpful?