Atrial Natriuretic Peptide Helps Regulate Blood Volume

Atrial natriuretic peptide (ANP) is a 28-amino acid polypeptide synthesized and stored in the atrial muscle cells and released into the bloodstream when the atria are stretched. By increasing sodium excretion, it decreases blood volume (see Chapter 24). It also inhibits renin release as well as aldosterone and AVP secretion. Increased ANP (along with decreased aldosterone and AVP) may be partially responsible for the reduction in blood volume that occurs with prolonged bed rest. When central blood volume and atrial stretch are increased, ANP secretion rises, leading to higher sodium excretion and a reduction in blood volume.

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Get Rid of Gallstones Naturally

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  • zemzem selam
    How doesatrial natriuretic regulate blood volume?
    8 years ago

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