Problems to Solve

1. Why are neural crest cells considered such an important cell population for craniofacial development?

2. You are called as a consultant for a child with a very small mandible and ears that are represented by small protuberances bilaterally. The baby has had numerous episodes ofpneumonia and is small for its age. What might your diagnosis be, and what might have caused these abnormalities?

3. A child is born with a median cleft lip. Shouldyou be concerned about any other abnormalities?

4. A child presents with a midline swelling beneath the arch of the hyoid bone. What might this swelling be, and what is its basis embryologically?

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