Preface

The ninth edition of Langman's Medical Embryology adheres to the tradition established by the original publication—it provides a concise but thorough description of embryology and its clinical significance, an awareness of which is essential in the diagnosis and prevention of birth defects. Recent advances inge-netics, developmental biology, maternal-fetal medicine, and public health have significantly increased our knowledge of embryology and its relevance. Because birth defects are the leading cause of infant mortality and a major contributor to disabilities, and because new prevention strategies have been developed, understanding the principles of embryology is important for health care professionals.

To accomplish its goal, Langman's Medical Embryology retains its unique approach of combining an economy of text with excellent diagrams and scanning electron micrographs. It reinforces basic embryologic concepts by providing numerous clinical examples that result from abnormalities in developmental processes. The following pedagogic features and updates in the ninth edition help facilitate student learning:

Organization of Material: Langman's Medical Embryology is organized into two parts. The first provides an overview of early development from gametogenesis through the embryonic period; also included in this section are chapters on placental and fetal development and prenatal diagnosis and birth defects. The second part of the text provides a description of the fundamental processes of embryogenesis for each organ system.

Molecular Biology: New information is provided about the molecular basis of normal and abnormal development.

Extensive Art Program: This edition features almost 400 illustrations, including new 4-color line drawings, scanning electron micrographs, and ultrasound images.

Clinical Correlates: In addition to describing normal events, each chapter contains clinical correlates that appear in highlighted boxes. This material is designed to provide information about birth defects and other clinical entities that are directly related to embryologic concepts.

Summary: At the end of each chapter is a summary that serves as a concise review of the key points described in detail throughout the chapter

Problems to Solve: These problems test a student's ability to apply the information covered in a particular chapter Detailed answers are provided in an appendix in the back of the book.

Simbryo: New to this edition, Simbryo, located in the back of the book, is an interactive CD-ROM that demonstrates normal embryologic events and the origins of some birth defects. This unique educational tool offers six original vector art animation modules to illustrate the complex, three-dimensional aspects of embryology. Modules include normal early development as well as head and neck, cardiovascular, gastrointestinal, genitourinary, and pulmonary system development.

Connection Web Site: This student and instructor site (http://connection. LWW.com/go/sadler) provides updates on new advances in the field and a syllabus designed for use with the book. The syllabus contains objectives and definitions of key terms organized by chapters and the "bottom line," which provides a synopsis of the most basic information that students should have mastered from their studies.

I hope you find this edition of Langman's Medical Embryology to be an excellent resource. Together, the textbook, CD, and connection site provide a user-friendly and innovative approach to learning embryology and its clinical relevance.

Twin Bridges, Montana one

General Embryology

General Embryology r

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