After ovulation, granulosa cells remaining in the wall of the ruptured follicle, together with cells from the theca interna, are vascularized by surrounding vessels. Under the influence of LH, these cells develop a yellowish pigment and change into lutean cells, which form the corpus luteum and secrete the hormone progesterone (Fig. 2.2C). Progesterone, together with estrogenic hormones, causes the uterine mucosa to enter the progestational or secretory stage in preparation for implantation of the embryo.
Figure 2.3 A. Scanning electron micrograph of ovulation in the mouse. The surface of the oocyte is covered by the zona pellucida. The cumulus oophorus is composed of granulosa cells. B. Scanning electron micrograph of a rabbit oocyte 1.5 hours after ovulation. The oocyte, which is surrounded by granulosa cells, lies on the surface of the ovary. Note the site of ovulation.
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