Steroids have complex anti-inflammatory and immunomodulatory effects. They inhibit migration of leucocytes to sites of inflammation, and interfere with the function of leucocytes, endothelial cells and fibroblasts. In addition, they suppress production and release of factors involved in the inflammatory response, including cytokines, prostaglandins and leukotrienes.
Steroids are metabolized in the liver. Their effects may be reduced by drugs that induce liver enzymes (eg, phenytoin, phenobarbitone and rifampicin). Blood levels of steroids may be raised in liver failure. Anticoagulant doses may need to be reduced when given concomitantly with steroids.
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Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.