B. Metabolic disorders associated with syndromes of calcium pyrophosphate dihydrate deposition include hyperparathyroidism, hemochromatosis, ochronosis, gout, hypomagnesemia, Wilson's disease, and hypophosphatasia. Other associations include aging, osteoarthritis, neuropathic joints, trauma, and septic arthritis.
VI. Treatment. In the acute attacks of pseudogout, a combination of joint aspiration and drug therapy is very beneficial. The affected joint should be mobilized quickly so that patients do not suffer complications from prolonged joint inactivity.
A. Joint aspiration alone removes a significant quantity of inciting crystals and chemical mediators, thereby often allowing the synovitis to subside. In those with protracted courses, intraarticular injection of a long-acting corticosteroid preparation is usually beneficial.
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