Deficiency of enzymes in the glycolytic pathway

Tue, 31 Jan 2012 | Rheumatoid Arthritis | 1 comment

Muscle phosphorylase deficiency McArdle disease . This inherited deficiency of skeletal muscle phosphorylase is more common than acid maltase deficiency or PFK deficiency 60 cases have been reported. The female-to-male ratio is 1 4. Childhood symptoms of fatigue are usually overlooked. A characteristic pattern of exercise-induced muscle pains, stiffness, and weakness, which resolves with rest, occurs after puberty. Prolonged exercise results in severe cramps of the exerted muscles....

Lupus erythematosus

Sat, 20 Aug 2011 | Rheumatoid Arthritis

The lupus band test LBT demonstrates deposits of immunoglobulin and complement at the dermal-epidermal junction by direct immunofluorescent staining of the skin. Biopsy of cutaneous lesions in DLE or systemic lupus erythematosus SLE yields a positive LBT in about 90 of patients. Clinically normal skin of patients with DLE demonstrates a negative LBT. The LBT in clinically normal skin of patients with SLE varies with sun exposure. Approximately 50 of patients with SLE have a positive LBT in...