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1. Nebel OT, Fornes MF, Castell DO. Symptomatic gastroesophageal reflux: incidence and precipitating factors. Am J Dig Dis 1976;21:953-956.

2. Gallup Organization. Gallup survey on heartburn across America, 1988.

3. Locke GR 3rd, Talley NJ, Fett SL, Zinmeister AR, Melton LJ 3rd. Prevalence and clinical spectrum of gas-troesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology 1997; 112:1448-1456.

4. El-Serag HB, Petersen NJ, Carter J, et al. Gastroe-sophageal reflux among different racial groups in the United States. Gastroenterology 2004;126:1692-1699.

5. DeMeester TR, Wang CI, Wernly JA, et al. Technique, indications, and clinical use of 24 hour esophageal pH monitoring. J Thorac Cardiovasc Surg 1980;79:656-670.

6. Johnsson F, Joelsson B, Gudmundsson K, Greiff L. Symptoms and endoscopic findings in the diagnosis of gastroesophageal reflux disease. Scand J Gastroenterol 1987;22:714-718.

7. Wienbeck M, Barnert J. Epidemiology of reflux disease and reflux esophagitis. Scand J Gastroenterol Suppl 1989; 156:7-13.

8. Cameron AJ, Zinsmeister AR, Ballard DJ, Carney JA. Prevalence of columnar-lined (Barrett's) esophagus: comparison of population-based clinical and autopsy findings. Gastroenterology 1990;99:918-922.

9. Bainbridge ET, Temple JG, Nicholas SP, Newton JR, Boriah V. Symptomatic gastro-oesophageal reflux in pregnancy: a comparative study of white Europeans and Asians in Birmingham. Br J Clin Pract 1983;37:53-57.

10. Sonnenberg A, El-Serag HB. Clinical epidemiology and natural history of gastroesophageal reflux disease. Yale J Biol Med 1999;72:81-92.

11. El-Serag HB, Sonnenberg A. Opposing time trends of peptic ulcer and reflux disease. Gut 1998;43:327-333.

12. El-Serag HB, Sonnenberg A, Jamal MM, Inadomi JM, Crooks LA, Feddersen RM. Corpus gastritis is protective against reflux oesophagitis. Gut 1999;45:181-185.

13. Graham DY. The changing epidemiology of GERD: geography and Helicobacter pylori. Am J Gastroenterol 2003;98:1462-1470.

14. Abe Y, Ohara S, Koike T, et al. The prevalence of Heli-cobacter pylori infection and the status of gastric acid secretion in patients with Barrett's esophagus in Japan. Am J Gastroenterol 2004;99:1213-1221.

15. Pandolfino JE, Howden CW, Kahrilas PJ. H. pylori and GERD: is less more? Am J Gastroenterol 2004;99: 1222-1225.


16. Dent J, Dodds WJ, Friedman RH, et al. Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J Clin Invest 1980;65:256-267.

17. Goyal RK, Rattan S. Genesis of basal sphincter pressure: effect of tetrodotoxin on lower esophageal sphincter pressure in opossum in vivo. Gastroenterology 1976;71: 62-67.

18. Goyal RK, Rattan S. Nature of the vagal inhibitory innervation to the lower esophageal sphincter. J Clin Invest 1975;55:1119-1126.

19. Yamato S, Saha JK, Goyal RK. Role of nitric oxide in lower esophageal sphincter relaxation to swallowing. Life Sci 1992;50:1263-1272.

20. Richards WG, Sugarbaker DJ. Neuronal control of esophageal function. Chest Surg Clin N Am 1995;5: 157-171.

21. Kahrilas PJ. Anatomy and physiology of the gastroe-sophageal junction. Gastroenterol Clin North Am 1997; 26:467-486.

22. Liebermann-Meffert D, Allgower M, Schmid P, Blum AL. Muscular equivalent of the lower esophageal sphincter. Gastroenterology 1979;76:31-38.

23. Thor KB, Hill LD, Mercer DD, Kozarek RD. Reappraisal of the flap valve mechanism in the gastroesophageal junction: a study of a new valvuloplasty procedure in cadavers. Acta Chir Scand 1987;153:25-28.

24. Hill LD, Kozarek RA, Kraemer SJ, et al. The gastroe-sophageal flap valve: in vitro and in vivo observations. Gastrointest Endosc 1996;44:541-547.

25. Mittal VK, Telmos AJ, Cortez JA. Surgical techniques for gastroesophagostomy with the EEA stapler. Int Surg 1985;70:29-32.

26. De Troyer A, Sampson M, Sigrist S, Macklem PT. Action of costal and crural parts of the diaphragm on the rib cage in dog. J Appl Physiol 1982;53:30-39.

27. Altschuler SM, Boyle JT, Nixon TE, Pack AI, Cohen S. Simultaneous reflex inhibition of lower esophageal sphincter and crural diaphragm in cats. Am J Physiol 1985;249:G586-G591.

28. Mittal RK, Fisher M, McCallum RW, Rochester DF, Dent J, Sluss J. Human lower esophageal sphincter pressure response to increased intra-abdominal pressure. Am J Physiol 1990;258:G624-G630.

29. Klein WA, Parkman HP, Dempsey DT, Fisher RS. Sphincterlike thoracoabdominal high pressure zone after esophagogastrectomy. Gastroenterology 1993;105: 1362-1369.

30. van Herwaarden MA, Samsom M, Smout AJ. Excess gas-troesophageal reflux in patients with hiatus hernia is caused by mechanisms other than transient LES relaxations. Gastroenterology 2000;119:1439-1446.

31. Holloway RH,Penagini R,Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995;268:G128-G133.

32. Mittal RK, Holloway RH, Penagini R, Blackshaw LA, Dent J. Transient lower esophageal sphincter relaxation. Gastroenterology 1995;109:601-610.

33. Sifrim D, Holloway R. Transient lower esophageal sphincter relaxations: how many or how harmful? Am J Gastroenterol 2001;96:2529-2532.

34. Sifrim D, Holloway R, Silny J, et al. Acid, nonacid, and gas reflux in patients with gastroesophageal reflux disease during ambulatory 24-hour pH-impedance recordings. Gastroenterology 2001;120:1588-1598.

35. Wyman JB, Dent J, Heddle R, Dodds WJ, Toouli J, Downton J. Control of belching by the lower oesophageal sphincter. Gut 1990;31:639-646.

36. Kahrilas PJ, Shi G, Manka M, Joehl RJ. Increased frequency of transient lower esophageal sphincter relaxation induced by gastric distention in reflux patients with hiatal hernia. Gastroenterology 2000;118:688-695.

37. Zagorodnyuk VP, Chen BN, Brookes SJ. Intraganglionic laminar endings are mechano-transduction sites of vagal tension receptors in the guinea-pig stomach. J Physiol 2001;534:255-268.

38. Zagorodnyuk VP, Chen BN, Costa M, Brookes SJ. Mechanotransduction by intraganglionic laminar endings of vagal tension receptors in the guinea-pig oesophagus. J Physiol 2003;553:575-587.

39. Martin CJ, Patrikios J, Dent J. Abolition of gas reflux and transient lower esophageal sphincter relaxation by vagal blockade in the dog. Gastroenterology 1986;91:890-896.

40. Martin CJ, Dodds WJ, Liem HH, Dantas RO, Layman RD, Dent J. Diaphragmatic contribution to gastroesophageal competence and reflux in dogs. Am J Physiol 1992;263: G551-G557.

41. Lehmann A, Antonsson M, Bremner-Danielsen M, Flardh M, Hansson-Branden L, Karrberg L. Activation of the GABA(B) receptor inhibits transient lower esophageal sphincter relaxations in dogs. Gastroen-terology 1999;117:1147-1154.

42. Lidums I, Lehmann A, Checklin H, Dent J, Holloway RH. Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects. Gastroenterology 2000;118:7-13.

43. van Herwaarden MA, Samsom M, Rydholm H, Smout AJ. The effect of baclofen on gastro-oesophageal reflux, lower oesophageal sphincter function and reflux symptoms in patients with reflux disease. Aliment Pharmacol Ther 2002;16:1655-1662.

44. Koek GH, Sifrim D, Lerut T, Janssens J, Tack J. Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors. Gut 2003;52:1397-1402.

45. Sloan S, Rademaker AW, Kahrilas PJ. Determinants of gastroesophageal junction incompetence: hiatal hernia, lower esophageal sphincter, or both? Ann Intern Med 1992;117:977-982.

46. Dent J, Dodds WJ, Hogan WJ, Toouli J. Factors that influence induction of gastroesophageal reflux in normal human subjects. Dig Dis Sci 1988;33:270-275.

47. Kahrilas PJ, Dodds WJ, Hogan WJ, Kern M, Arndorfer RC, Reece A. Esophageal peristaltic dysfunction in peptic esophagitis. Gastroenterology 1986;91:897-904.

48. Mittal RK, Rochester DF, McCallum RW. Effect of the diaphragmatic contraction on lower oesophageal sphincter pressure in man. Gut 1987;28:1564-1568.

49. Kahrilas PJ, Lin S, Chen J, Manka M. The effect of hiatus hernia on gastro-oesophageal junction pressure. Gut 1999;44:476-482.

50. Marchand P. The surgery for hiatus hernia: is vagotomy rational? S Afr Med J 1970;44:35-39.

51. Michelson E, Siegel C. The role of the phrenico-esophageal ligament in the lower esophageal sphincter. Surg Gynecol Obstet 1964;118:1291-1294.

52. Kahrilas PJ, Lin S, Manka M, Shi G, Joehl RJ. Esopha-gogastric junction pressure topography after fundopli-cation. Surgery 2000;127:200-208.


53. Stein HJ, DeMeester TR, Naspetti R, Jamieson J, Perry RE. Three-dimensional imaging of the lower esophageal sphincter in gastroesophageal reflux disease. Ann Surg 1991;214:374-383; discussion 383-384.

54. Contractor QQ, Akhtar SS, Contractor TQ. Endoscopic esophagitis and gastroesophageal flap valve. J Clin Gastroenterol 1999;28:233-237.

55. Pandolfino JE, Bianchi L, Lee TJ, Hirano I, Kahrilas PJ. Esophagogastric junction morphology predicts susceptibility to exercise-induced reflux. Am J Gastroenterol 2004;99:1430-1436.

56. Pandolfino JE, Shi G, Trueworthy B, Kahrilas PJ. Esophagogastric junction opening during relaxation distinguishes nonhernia reflux patients, hernia patients, and normal subjects. Gastroenterology 2003;125: 1018-1024.

57. Curry J, Shi G, Pandolfino JE, Joehl RJ, Brasseur JG, Kahrilas PJ. Mechanical characteristics of the EGJ after fundoplication compared to normal subjects and GERD patients. Gastroenterology 2001;120:A112.

58. Helm JF. Role of saliva in esophageal function and disease. Dysphagia 1989;4:76-84.

59. Schneyer LH, Pigman W, Hanahan L, Gilmore RW. Rate of flow of human parotid, sublingual, and submaxillary secretions during sleep. J Dent Res 1956;35:109-114.

60. Singh S, Bradley LA, Richter JE. Determinants of oesophageal "alkaline" pH environment in controls and patients with gastro-oesophageal reflux disease. Gut 1993;34:309-316.

61. Borchardt PJ. Employee productivity and gastroe-sophageal reflux disease: the payer's viewpoint. Am J Gastroenterol 2001;96:S62-S63.

62. Stanciu C, Bennett JR. Oesophageal acid clearing: one factor in the production of reflux oesophagitis. Gut 1974;15:852-857.

63. Dodds WJ, Kahrilas PJ, Dent J, et al. Analysis of spontaneous gastroesophageal reflux and esophageal acid clearance in patients with reflux esophagitis. J Gas-trointest Motil 1990;2:79.

64. Johnson LF. Twenty-four-hour pH monitoring in the study of gastroesophageal reflux. J Clin Gastroenterol 1980;2:387-399.

65. Gillen P, Keeling P, Byrne PJ, Hennessy TP. Barrett's oesophagus: pH profile. Br J Surg 1987;74:774-776.

66. Karvelis KC, Drane WE, Johnson DA, Silverman ED. Barrett esophagus: decreased esophageal clearance shown by radionuclide esophageal scintigraphy. Radiology 1987;162:97-99.

67. Singh P, Adamopoulos A, Taylor RH, Colin-Jones DG. Oesophageal motor function before and after healing of oesophagitis. Gut 1992;33:1590-1596.

68. Kahrilas PJ, Dodds WJ, Hogan WJ. Effect of peristaltic dysfunction on esophageal volume clearance. Gastroen-terology 1988;94:73-80.

69. Leite LP, Johnston BT, Barrett J, Castell JA, Castell DO. Ineffective esophageal motility (IEM): the primary finding in patients with nonspecific esophageal motility disorder. Dig Dis Sci 1997;42:1859-1865.

70. Timmer R, Breumelhof R, Nadorp JH, Smout AJ. Oesophageal motility and gastro-oesophageal reflux before and after healing of reflux oesophagitis: a study using 24 hour ambulatory pH and pressure monitoring. Gut 1994;35:1519-1522.

71. Rydberg L, Ruth M, Lundell L. Does oesophageal motor function improve with time after successful anti-reflux surgery? Results of a prospective, randomised clinical study. Gut 1997;41:82-86.

72. Mittal RK, Lange RC, McCallum RW. Identification and mechanism of delayed esophageal acid clearance in subjects with hiatus hernia. Gastroenterology 1987;92:130-135.

73. Sloan S, Kahrilas PJ. Impairment of esophageal emptying with hiatal hernia. Gastroenterology 1991;100: 596-605.

74. Korsten MA, Rosman AS, Fishbein S, Shlein RD, Goldberg HE, Biener A. Chronic xerostomia increases esophageal acid exposure and is associated with esophageal injury. Am J Med 1991;90:701-706.

75. Kahrilas PJ, Gupta RR. The effect of cigarette smoking on salivation and esophageal acid clearance. J Lab Clin Med 1989;114:431-438.

76. Konturek JW, Bielanski W, Konturek SJ, Bogdal J, Oleksy J. Distribution and release of epidermal growth factor in man. Gut 1989;30:1194-1200.

77. Skoner DP. Growth effects of asthma and asthma therapy. Curr Opin Pulm Med 2002;8:45-49.

78. Sarosiek J, Feng T, McCallum RW. The interrelationship between salivary epidermal growth factor and the functional integrity of the esophageal mucosal barrier in the rat. Am J Med Sci 1991;302:359-363.

79. Maccini DM, Veit BC. Salivary epidermal growth factor in patients with and without acid peptic disease. Am J Gastroenterol 1990;85:1102-1104.

80. Rourk RM, Namiot Z, Sarosiek J, Yu Z, McCallum RW. Impairment of salivary epidermal growth factor secretory response to esophageal mechanical and chemical stimulation in patients with reflux esophagitis. Am J Gastroenterol 1994;89:237-244.

81. Pandolfino JE, Kahrilas PJ. Esophagel motility abnormalities in barrett's esophagus. In: Sharma P, Sampliner RE, eds. Barrett's Esophagus and Esophageal Adenocar-cinoma. Malden, MA: Blackwell Science; 2001:35-44.

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