Medical Management of GERD Algorithms and Outcomes

David A. Johnson

Therapeutic efficacy of treatments for gastroe-sophageal reflux disease (GERD) has been measured using a variety of different endpoints. Across the surgical, endoscopic, and pharmacological treatment interventions for GERD, an attempt has been made to measure the therapeutic effect of these interventions by both objective and subjective means. This has included objective measures such as the effect a treatment has on esophageal sphincter pressure, intraesophageal acid exposure, and endoscopic esophagitis. Subjective measures of effect have included symptom response as assessed by questionnaires, symptom severity scales, physician assessment, and quality-of-life impact. Despite the innumerable studies reporting various treatment interventions for GERD, overall there is a general lack of use of standardized methodology that would allow comparison of the relative success achieved between the various therapies. Furthermore, there is a striking lack of use of validated instruments to accurately assess treatment effect in many of these studies. This review focuses on the questions that should be raised by clinicians in order for them to apply an evidence-based evaluation of the outcomes achieved in these GERD intervention trials.

Herbal Remedies For Acid Reflux

Herbal Remedies For Acid Reflux

Gastroesophageal reflux disease is the medical term for what we know as acid reflux. Acid reflux occurs when the stomach releases its liquid back into the esophagus, causing inflammation and damage to the esophageal lining. The regurgitated acid most often consists of a few compoundsbr acid, bile, and pepsin.

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