In order to relate tissue remodeling in HPH to blood pressure and flow, the simplified solutions discussed in the preceding section tell us to focus our attention on both the mean level of blood pressure and the oscillations about the mean. Looking at the actual recording as shown in Figure 2, we find that the task is not as easy as it appears. We know the signals vary with the location along the vascular tree. At any given point on the tree, the signals are never exactly periodic. Arrhythmia exists to some degree all the time at all places. Mathematicians call such signals nonstationary and stochastic, and a very large literature exists to deal with such signals. Well known methods are associated with names such as functional Fourier analysis, Fourier spectrum, Hilbert
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