An ideal technology to directly characterize protein-ligand binding would have the following properties: (1) it would require no labeling of the target or small molecules with radioisotopes, fluorophores, or other moieties, and no covalent modification to immobilize the protein target or small molecules on a surface would be necessary; (2) the ideal technique could selectively identify the compound that is responsible for the observed output; (3) it would be solution-based, and amenable to all cofactors, salts, metal ions, and detergents necessary for proper protein folding and stability; and (4) it would require only modest amounts of a purified protein target for its implementation.
Was this article helpful?
Thousands Have Used Chemicals To Improve Their Medical Condition. This Book Is one Of The Most Valuable Resources In The World When It Comes To Chemicals. Not All Chemicals Are Harmful For Your Body – Find Out Those That Helps To Maintain Your Health.