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1 A. Smith: Screening for drug discovery: the leading question. Nature 2002, 418, 453-459.

4 C. Enjalbal, J. Martinez, J. L. Aubagnac: Mass spectrometry in combinatorial chemistry. Mass Spectrom Rev 2000, 19, 139-161.

throughput screening. J Chromatogr B Biomed Sci Appl 1999, 725, 67-78.

2 K. Robards: Strategies for the determination of bioactive phenols in plants, fruit and vegetables. J Chromatogr A 2003, 1000, 657691.

5 V. Swali, G. J. Langley, M. Bradley: Mass spectrometric analysis in combinatorial chemistry. Curr Opin Chem Biol 1999, 3, 337-341.

3 M. A. Strege: High-performance liquid chromatographic-electrospray ionization mass spectrometric analyses for the integration of natural products with modern high-

6 K. J. Miller, A. C. Herman: Affinity chromatography with immuno-chemical detection applied to the analysis of human methionyl granulocyte colony stimulating factor in serum. Anal Chem 1996, 68, 3077-3082.

7 A. J. Oosterkamp, M. T. Villaverde Herraiz, H. Irth, U. R. Tjaden, J. van der Greef: Reversed-phase liquid chromatography coupled on-line to receptor affinity detection based on the human estrogen receptor. Anal Chem 1996, 68, 1201-1206.

8 T. Schenk, G. J. Breel, P. Koevoets, S. van den Berg, A. C. Hogenboom, H. Irth, U. R. Tjaden, J. van der Greef: Screening of natural products extracts for the presence of phosphodiesterase inhibitors using liquid chromatog-raphy coupled online to parallel biochemical detection and chemical characterization. J Biomol Screen 2003, 8, 421-429.

9 A. Belenky, D. Hughes, A. Korneev, Y. Dunayevskiy: Capillary electrophoretic approach to screen for enzyme inhibitors in natural extracts.

J ChromatogrA 2004, 1053, 247-251.

10 H. Y. Cheung, W. P. Lai, M. S. Cheung, F. M. Leung, D. J. Hood, W. F. Fong: Rapid and simultaneous analysis of some bioactive components in Eucommia ulmoides by capillary electrophoresis. J Chromatogr A 2003, 989, 303-310.

11 L. Ma, X. Gong, E. S. Yeung: Combinatorial screening of enzyme activity by using multiplexed capillary electrophoresis. Anal Chem 2000, 72, 3383-3387.

12 Y. F. Hsieh, N. Gordon, F. Regnier, N. Afeyan, S. A. Martin, G. J. Vella: Multidimensional chromatography coupled with mass spectrometry for target-based screening. Mol Diversity 1997, 2, 189-196.

13 K. Ingkaninan, C. M. de Best, R. van der Heijden, A. J. Hofte, B. Karabatak, H. Irth, U. R. Tjaden,

J. van der Greef, R. Verpoorte: Highperformance liquid chromatography with on-line coupled UV, mass spectrometric and biochemical detection for identification of acetylcholinesterase inhibitors from natural products. J Chromatogr A 2000, 872, 61-73.

14 G. R. Lenz, H. M. Nash, S. Jindal: Chemical ligands, genomics and drug discovery. Drug Discov Today 2000, 5, 145-156.

15 U. Schobel, M. Frenay, D. A. van Elswijk, J. M. McAndrews, K. R. Long, L. M. Olson, S. C. Bobzin, H. Irth: High resolution screening of plant natural product extracts for estrogen receptor alpha and beta binding activity using an online HPLC-MS biochemical detection system. J Biomol Screen 2001, 6, 291-303.

16 D. A. van Elswijk, O. Diefenbach, S. van der Berg, H. Irth, U. R. Tjaden, J. van der Greef:Rapid detection and identification of angiotensin-converting enzyme inhibitors by on-line liquid chromatography-biochemical detection, coupled to electrospray mass spectrometry.

J Chromatogr A 2003, 1020, 45-58.

17 A. R. de Boer, T. Letzel, D. A. van Elswijk, H. Lingeman, W. M. Niessen, H. Irth: On-line coupling of high-performance liquid chromatog-raphy to a continuous-flow enzyme assay based on electrospray ionization mass spectrometry. Anal Chem 2004, 76, 3155-3161.

18 E. Shaw, R. T. Dean: The inhibition of macrophage protein turnover by a selective inhibitor of thiol proteinases. Biochem J 1980, 186, 385-390.

19 L. Herszenyi, M. Plebani, P. Carraro, M. De Paoli, G. Roveroni, R. Cardin, F. Foschia, Z. Tulassay, R. Naccarato, F. Farinati: Proteases in gastrointestinal neoplastic diseases. Clin Chim Acta 2000, 291, 171-187.

20 J. E. Koblinski, M. Ahram, B. F. Sloane: Unraveling the role of proteases in cancer. Clin Chim Acta 2000, 291, 113-135.

21 R. Bonfiglio, R. C. King, T. V. Olah, K. Merkle: The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds. Rapid Commun Mass Spectrom 1999, 13, 1175-1185.

22 C. F. de Jong, R. J. Derks, B. Bruyneel, W. Niessen, H. Irth: High-

performance liquid chromatography-mass spectrometry-based acetylcholinesterase assay for the screening of inhibitors in natural extracts. J ChromatogrA 2006, 1112, 303-310.

23 R. T. Bartus, R. L. Dean 3rd, B. Beer, A. S. Lippa: The cholinergic hypothesis of geriatric memory dysfunction. Science 1982, 217, 408-414.

24 H. M. Greenblatt, H. Dvir, I. Silman, J. L. Sussman: Acetylcholinesterase: a multifaceted target for structure-based drug design of anticholines-terase agents for the treatment of Alzheimer's disease. J Mol Neurosci 2003, 20, 369-383.

25 M. Heinrich, H. L. Teoh: Galanth-amine from snowdrop - the development of a modern drug against Alzheimer's disease from local Caucasian knowledge. J Ethno-pharmacol 2004, 92, 147-162.

26 I. K. Rhee, N. Appels, T. Luijendijk, H. Irth, R. Verpoorte: Determining acetylcholinesterase inhibitory activity in plant extracts using a fluorimetric flow assay. Phytochem Anal 2003, 14, 145-149.

27 A. R. de Boer, B. Bruyneel, J. G. Krabbe, H. Lingeman, W. M. Niessen, H. Irth: A microfluidic-based enzymatic assay for bioactivity screening combined with capillary liquid chromatography and mass spectrometry. Lab Chip 2005, 5, 1286-1292.

28 A. C. Hogenboom, A. R. de Boer, R. J. Derks, H. Irth: Continuous-flow, on-line monitoring of biospecific interactions using electrospray mass spectrometry. Anal Chem 2001, 73, 3816-3823.

29 R. J. Derks, A. C. Hogenboom, G. van der Zwan, H. Irth: On-line continuous-flow, multi-protein biochemical assays for the characterization of bioaffinity compounds using electrospray quadrupole time-of-flight mass spectrometry. Anal Chem 2003, 75, 3376-3384.

30 D. A. van Elswijk, U. R. Tjaden, J. van der Greef,H. Irth: Mass spectrometry-based bioassay for the screening of soluble orphan receptors. Int J Mass Spectrom 2001, 210/211, 625-636.

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