Stability of Fostriecin

In whole blood, fostriecin was found to be stable for the first 2 h, and aqueous fostriecin remained stable for approximately 12 days. Fostriecin concentration in frozen (-20°C) plasma samples decreased after approximately 14 days. The decrease in fostriecin concentration was not affected by adding ascorbic acid to protect the samples from oxidation. At -70°C samples remained stable for approximately 49 days; stability decreased rapidly thereafter (Pillon et al. 1994).

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