Ggatcactc Cctagtgag

| When 5-methylcytosine loses its amino group, thymine results. Since this is a normal DNA base, it is not repaired.

Methyl >.N group

| When 5-methylcytosine loses its amino group, thymine results. Since this is a normal DNA base, it is not repaired.

17.8 5-Methylcytosine in DNA Is a "Hot Spot" for Mutagenesis

(a) Cytosine can lose an amino group either spontaneously or because of exposure to certain chemical mutagens. Such mutations are usually repaired. (b) If the cytosine residue has been methylated to 5-methylcytosine, however, the mutation is unlikely to be repaired.

17.8 5-Methylcytosine in DNA Is a "Hot Spot" for Mutagenesis

(a) Cytosine can lose an amino group either spontaneously or because of exposure to certain chemical mutagens. Such mutations are usually repaired. (b) If the cytosine residue has been methylated to 5-methylcytosine, however, the mutation is unlikely to be repaired.

but adjacent genes as well; the result may be several diseases simultaneously.

Was this article helpful?

0 0
Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

Get My Free Ebook


Post a comment