Altered membrane proteins cause many diseases

Some of the most common human genetic diseases show their primary phenotype as altered membrane receptor and transport proteins. About one person in 500 is born with familial hypercholesterolemia (FH), in which levels of cholesterol in the blood are several times higher than normal. The excess cholesterol can accumulate on the inner walls of blood vessels, leading to complete blockage if a blood clot forms. If a clot forms in a major vessel serving the heart, the heart becomes starved of oxygen, and a heart attack results. If a

Amino acid position (of 146) 2 6 7 16 24 26 56 63 95 A (Wild type) His Glu Glu Gly Gly Glu Gly His Lys

Was this article helpful?

0 0
Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

Get My Free Ebook


Post a comment