Prolactin (PRL) has a short half-life of hours, and a single postoperative level in the normal range can be considered indicative of a cure. If the level is in the 700-1000 mU/L range, this may represent a cure, because PRL levels can be increased by the stress of the procedure and by perioperative antiemetics. It is worth repeating: If the level remains high, when surgery was expected to be successful and particularly if the tissue taken at surgery was histologically confirmed, then reoperation is strongly advised.

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