How to Cure Chronic Pelvic Pain

Endometriosis and Infertility Solution

Health researcher, Shelly Ross is the author of Treating Your Endometriosis and in her remarkable eBook, she will walk you through practical methods to successfully control and manage endometriosis once and for all. In her Treating Your Endometriosis eBook Shelly talks about the endometriosis diet that is a key factor in addressing endometriosis pain and symptoms. Endometriosis is not something to be taken lightly. If you suspect that you may have endometriosis you should immediately seek medical advice for a diagnosis. While there is no cure for the disease, it is possible to treat it through a variety of treatments. Read more here...

Treating Your Endometriosis Summary


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Author: Shelley Ross
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Endometriosis Bible & Violet Protocol

Zoe Brown's guide promises to end your endometriosis in a matter of weeks, or less. She shows you how to do this without the aid of dangerous drugs. She also demonstrates how to. conquer the effects of endometriosis in pregnancy. Zoe Brown's plan supplies a 5-step Violet Protocol that has been formally shown to entirely get rid of cysts, adhesions, lesions, and all sorts of other indications of endometriosis. The actual Endometriosis Bible & Violet Protocol additionally points out the reasons why entirely no exceptional diet or detox plan will supply a real treatment to your endometriosis and why just some specific unpopular herbal treatments might have a good impact upon endometriosis. If you are suffering from the condition of endometriosis, you should grab the Zoe Browns Endometriosis Bible And Violet Protocol right now for various reasons. Becoming an alternative treatment, Violet Protocol is actually much better than taking pharmaceutical medicine or having surgery. Read more here...

Endometriosis Bible & Violet Protocol Summary

Contents: 303 Pages EBook
Author: Zoe Brown
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Price: $47.00

Why Proteomics Has Not Succeeded In The Past Cancer As An Example

The inability of these protein biomarkers to detect all cancers (false negatives) reflects both the progressive nature of cancer and its heterogeneity. Cancer is not a single disease but rather an accumulation of several events, genetic and epigenetic, arising in a single cell over a long period of time. Proteins overexpressed in late stage cancers may not be overexpressed in earlier stages and, therefore, are not useful for early cancer detection. For example, the CA125 antigen is not highly expressed in many Stage I ovarian cancers. Also, because tumors are heterogeneous, the same sets of proteins are not necessarily overexpressed in each individual tumor. For example, while most patients with high-grade prostate cancers have increased levels of PSA, approximately 15 of these patients do not have an elevated PSA level. The reciprocal problem of biomarkers indicating the presence of cancer when none is present (false positives) results because these proteins are not uniquely produced...

Gram Positive Anaerobic Cocci

Gram-positive, strictly anaerobic cocci are included in the genera Peptococcus and Peptostreptococcus. The only species in the first genus is Peptococcus niger, whereas the latter comprises a number of species. The anaerobic cocci are commonly observed in normal human flora. In a pathogenic context they are usually only encountered as components of mixed florae together with other anaerobes or facultative anaerobes. These bacteria invade tissues through dermal or mucosal injuries and cause subacute purulent infections. Such infections are either localized in the head area (cerebral abscess, otitis media, mastoiditis, sinusitis) or lower respiratory tract (necrotizing pneumonia, pulmonary abscess, empyema). They are also known to occur in the abdomen (appendicitis, peritonitis, hepatic abscess) and female genitals (salpin-gitis, endometriosis, tubo-ovarian abscess). Gram-positive anaerobic cocci may also contribute to soft-tissue infections and postoperative wound infections. See p....

Diseases of the genitourinary system N00N99

Endometriosis N80.0 Endometriosis of uterus Adenomyosis N80.1 Endometriosis of ovary N80.2 Endometriosis of fallopian tube N80.3 Endometriosis of pelvic peritoneum N80.4 Endometriosis of rectovaginal septum and vagina N80.5 Endometriosis of intestine N80.6 Endometriosis in cutaneous scar N80.8 Other endometriosis N80.9 Endometriosis, unspecified

Restrict Inference to Disease Outcome That Can Be Ascertained Accurately

Endometriosis, in which there is endometrial tissue located at abnormal anatomic locations in the abdominal cavity, is quite common and largely undetected, but the form of the disease that is more extensive appears to be more likely to produce symptoms that lead to diagnosis. Some of the confusion is semantic, i.e., whether disease is truly present when the requisite biologic changes have occurred but there are no overt symptoms and such symptoms may never arise. For studying etiology, however, the biologic entity itself is often of primary interest, so that variability in symptom occurrence, recognition, care-seeking, and ultimately disease diagnosis represent opportunities for misclassification. An accurate diagnosis often requires many steps, as discussed above, but the probability of all those events occurring is often highest when the disease is most severe in terms of stage or scope. The most informative approach to the study of diseases with a spectrum...

Protein Macromolecules

Of such macromolecules and other serum components varies between patients and even within the menstrual cycle, it makes any comparison between batches of medium which contain serum almost impossible. Furthermore, serum from several groups of patients such as those with endometriosis, PCO or unexplained infertility appears to be embryo-toxic (186-190). There are several reasons for the elimination of serum from mammalian embryo culture systems. From a physiological perspective the mammalian embryo is never exposed to serum in vivo. The fluids of the female reproductive tract are not simple serum transudates (191), but rather specialized environments for the development of the embryo (30). Serum can best be considered a pathological fluid formed by the action of platelets. More disturbing however, is the growing evidence that serum is detrimental to the developing mammalian preimplanta-tion embryo in culture. Studies on the embryos of mice, sheep and cattle have demonstrated that serum...

Contraceptive Hormones

Taking the contraceptive hormones provides health benefits not related to contraception, such as regulating the menstrual cycle and decreased blood loss, and incidence of iron deficiency anemia, and dysmenorrhea. Health benefits related to the inhibition of ovulation include a decrease in ovarian cysts and ectopic pregnancies. In addition, there is a decrease in fibrocyctic breast disease, acute pelvic inflammatory disease, endometrial cancer, ovarian cancer, maintenance of bone density, and symptoms related to endometriosis in women taking contraceptive hormones. Newer combination contraceptives such as norgestimate and ethinyl estradiol

Clinical Focus Box 391

Candidates for in vitro fertilization (IVF) are women with disease of the oviducts, unexplained infertility, or endometriosis (occurrence of endometrial tissue outside the endometrial cavity, a condition that reduces fertility), and those whose male partners are infertile (e.g., low sperm count). Follicular development is induced with one or a combination of GnRH analogs, clomiphene, recombinant FSH, and menopausal gonadotropins (a combination of LH and FSH). Follicular growth is monitored by measuring serum estradiol concentration and by ultrasound imaging of the developing follicles. When the leading follicle is 16 to 17 mm in diameter and or the estradiol level is greater than 300 pg mL, hCG is injected to mimic an LH surge and induce final follicular maturation, including maturation of the oocyte. Approximately, 34 to 36 hours later, oocytes are retrieved from the larger follicles by aspiration using laparoscopy or a

Spermatogenesis Stimulation

Testosterone And Prenatal Development

Because the sperm concentration usually remains below the normal range, evaluation, and optimization of the female partner's reproductive functions is indispensable, because the fecundity of a couple is dependent on both male and female reproductive function (43). An evaluation of the female cycle quality should be performed, and if pregnancy is not achieved after 6 mo, tubal function should be checked. Furthermore, hormonal disturbances such as polycystic ovary syndrome (PCOs), endometriosis, and other gynecological or systemic diseases can lead to female infertility (44). It is also well-known that the time span within which a couple will conceive ( time to preg-

Reproductive technologies help solve problems of infertility

There are many reasons why a man and woman may not be able to have children. The man's rate of sperm production may be low, or his sperm may lack motility. The mucus in the woman's reproductive tract may be thick and not conducive to sperm reaching the oviducts. Structural problems may also exist, such as blockage of the oviducts by scar tissue or by endometriosis, a proliferation of endometrial cells outside of the uterus. In some cases, treatment with powerful chemicals to cure cancer damages the ability of the go-nads to produce gametes.

Examples of Prostaglandin Actions

Prostaglandins may play a role in ovulation and corpus luteum function in the ovaries and in contraction of the uterus. Excessive production of PGE2 and PGI2 may be involved in premature labor, endometriosis, dysmenorrhea (painful menstrual cramps), and other gynecological disorders.

Outcomes After Laparoscopic Adhesiolysis

The use of laparoscopy to treat adhesions is not new. Adhesiolysis using a laparoscope has been performed by gynecologists decades ago (before videolaparoscopy) to treat chronic pelvic pain or infertility related to fallopian tube obstruction. Currently, complex and extensive adhesiolysis is feasible using laparoscopic techniques, thus surgeons have adopted this minimally invasive approach to treat abdominal pain or bowel obstruction in selected patients. This chapter will review the evidence base related to these two indications.

KIR Contribution to Maternal Fetal Bonding

EVT express an unusual combination of HLA class I molecules, HLA-G, HLA-E and HLA-C (Hiby et al. 1999 King et al. 2000a,b), and they do not express the polymorphic HLA-A and HLA-B that are found on most other nucleated cells of the body (Goodfellow et al. 1976). Uterine NK cells are distinct from blood-derived NK cells in that a greater proportion of uNK express KIR molecules that bind HLA-C allotypes relative to NK cells circulating in the periphery (Hiby et al. 1997 Verma et al. 1997). Alterations in KIR expression among women with diseases of the reproductive tract, including endometriosis, adenomyosis, and anembryonic pregnancy, have been described (Chao et al. 1999 Wu et al. 2000 Maeda et al. 2002, 2004 Yang et al. 2004), generating further speculation of a potential role for these molecules in disease pathogenesis of the uterus. Understanding the interactions between these receptor-ligand pairs during pregnancy and their role in securing harmonious interactions between the...

Pelvic Inflammatory Disease

Pelvic inflammatory disease (PID) remains a diagnostic and treatment challenge. It is typically defined as an infection of the female genital tract above the cervix and may include salpingitis, endometritis, tubuloovarian abscess (TOA), and or frank peritonitis (64). Long-term sequelae of PID are severe and include ectopic pregnancy, infertility, and chronic pelvic pain (64). In the United States, the population most commonly affected by PID appears to be the young, nonwhite, unmarried urban dweller as well as those with a history of PID, multiple sexual partners, previous or current STDs, and cigarette smoking (64). Controversy surrounds the role of IUDs and douching as risk factors for PID (64). The diagnosis of PID is imprecise and should be considered in any woman with pelvic pain. Definitive diagnosis can be made by culture of involved areas, but this frequently involves invasive procedures such as culdocentesis, endometrial biopsy, and or laparoscopy. The differential diagnosis...

Clinical Aspects of Pregnancy and Birth

Ectopic Pregnancy Birth

Development of a fertilized egg outside of its normal position in the uterine cavity is termed an ectopic pregnancy (Fig. 15-12). Although it may occur elsewhere in the abdominal cavity, this abnormal development usually takes place in the oviduct, resulting in a tubal pregnancy. Salpingitis, endometriosis, and PID may lead to ectopic pregnancy by blocking passage of the egg into the uterus. Continued growth will rupture the oviduct, causing dangerous hemorrhage. Symptoms of ectopic pregnancy are pain, tenderness, swelling,

Special Considerations

Ureteral injuries are one of the most important complications, which can be avoided by a perfect exposure and the respect of the correct plane of dissection. Indeed, a dissection properly performed above the Toldt's fascia does not expose the ureter to accidental injury. Difficult cases, such as important inflammatory reaction, cancer invasion or adhesions, and, sometimes, endometriosis, may alter the anatomy of the region and render the identification of the ureter troublesome. In these special cases, prevention of ureteral injury may be facilitated by the use of infrared wires inserted in ureteral stents. The infrared light is cold and safe for use in close contact with the ureteral tissue, and, on the other side, makes it easy to recognize the structure under the light of an adequate laparoscope.

Serum Prolactin

The measurement of serum prolactin is a useful blood test in diagnosing seizure disorders. Prolactin is a polypeptide hormone produced by the anterior pituitary, involved in milk production and endocrine function. Unlike most pituitary hormones, prolactin is under negative hypothalamic control via prolactin inhibiting factor. When seizure activity influences the hypothalamic-pitu-itary axis, prolactin inhibiting factor is presumed to be inhibited itself, and prolactin is released into the circulation. Trimble (105) first showed that serum prolactin rises with generalized epileptic seizures, but not with psy-chogenic seizure-like episodes. Complex partial seizures can also raise serum prolactin. Sensitivity is approximately 90 for tonic-clonic seizures and 70 for complex partial seizures (106). Complex partial seizures originating in the frontal lobes rarely elevate serum pro-lactin (89,90), again emphasizing the difficulty in diagnosis of frontal lobe epilepsy. Several conditions can...

Poor Responders

Poor responders to exogenous gonadotropins require markedly increased quantities of gonadotropins to obtain multifollicular development. Moreover, the number of oocytes, fertilization rates, embryo quality, and pregnancy rates are all decreased in this patient population. The incidence of poor response varies from 5 to 18 of unselected IVF patients (70). Poor response to gonadotropins is a result of diminished ovarian reserve. The most important cause is advanced female age. An age-related decline in fecundity, from 35 years in particular, has been observed in IVF. Other causes are prior chemotherapy, irradiation, ovarian surgery, severe endometriosis, autoimmune disease, or idiopathic. Some patients present with unexplained infertility and regular ovulatory cycles.

51 Tips for Dealing with Endometriosis

51 Tips for Dealing with Endometriosis

Do you have Endometriosis? Do you think you do, but aren’t sure? Are you having a hard time learning to cope? 51 Tips for Dealing with Endometriosis can help.

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