As newer reperfusion strategies are reported to achieve a higher incidence of TIMI grade 3 flow, a categorical scale may fail to distinguish their efficacies because there is a range of dye velocities that constitute TIMI grade 3 flow (2,36-38). Even if two reperfusion strategies result in the same proportion of TIMI grade 3 flow, the TIMI grade 3 flow of one strategy may be faster than the TIMI grade 3 flow of another strategy, and there may be a difference in the dye velocity between the two strategies when analyzed as a continuous variable using the CTFC. This range of velocities that constitutes TIMI grade 3 flow can be demonstrated by the following example (37). We have developed a new method of measuring absolute velocity called the PTCA guidewire velocity (37).
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