References

1 Von Behring, E. and Kitasato, S. (1890) Über das Zustandekommen der Diphtherie-Immunität und der Tetanus-Immunität bei Thieren. Deutsche Medizinische Wochenzeitschrift 16, 1113-1114.

2. Köhler, G. and Milstein, C. (1975) Continous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495-497.

3 Winter, G. and Milstein, C. (1991) Man-made antibodies. Nature 349,293-299.

4 Jakobovits, A. (1995) Production of fully human antibodies by transgenic mice. Curr. Opin. Biotechnol. 6, 561-566.

5 Lonberg, N. and Huszar, D. (1995) Human antibodies from transgenic mice. Int. Rev. Immunol. 13, 65-93.

6 Fishwild, D. M., O'Donnel, S. L., Bengoechea, T., Hudson, D. V., Harding, F., Bernhar, S. L., et al. (1996) High-avidity human IgG

kappa monoclonal antibodies from a novel strain of minilocus transgenic mice. Nat. Biotech. 14, 845-851.

7 Huse, W. D., Sastry, L., Iverson, S. A., Kang, A. S., Alting-Mees, M., Burton, D. R., et al. (1989) Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 246, 1275-1281.

8 Persson, M. A. A., Caothien, R. H., and Burton, D. R. (1991) Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning. Proc. Natl. Acad. Sci. USA 88, 2432-2436.

9 Smith, G. P. (1985) Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 228, 1315-1317.

10 McCafferty, J., Griffiths, A. D., Winter, G., and Chiswell, D. J.

(1990) Phage antibodies: filamentous phage displaying antibody variable domain. Nature 348, 552-554.

11. Barbas III, C. F., Kang, A. S., Lerner, R. A., and Benkovic, S. J.

(1991) Assembly of combinatorial antibody libraries on phages surfaces: the gene III site. Proc. Natl. Acad. Sci. USA 88, 7987-7982.

12 Breitling, F., Dübel, S., Seehaus, T., Kleewinghaus, I., and Little, M. (1991) A surface expression vector for antibody screening. Gene 104,1047-1153.

13. Clackson, T., Hoogenboom, H. R., Griffiths, A. D., and Winter, G. (1991) Making antibody fragments using phage display libraries. Nature 352, 624-628.

14 Hoogenboom, H. R., Griffiths, A. D., Johnson, K. S., Chiswell, D. J., Hudson, P., and Winter, G. (1991) Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucl. Acids Res. 19, 4133-4137.

15 Marks, J. D., Hoogenboom, H. R., Bonnert, T. P., McCafferty, J., Griffiths, A. D., and Winter, G. (1991) By-passing immunization: human antibodies from V-gene libraries diplayed on phage. J. Mol. Biol. 222, 581-597.

16 Sblattero, D. and Bradbury, A. (2000) Exploiting recombination in single bacteria to make large phage antibody libraries. Nat. Biotech. 18, 75-80.

17 Hust, M. and Dübel, S. (2004) Mating antibody phage display to proteomics. Trends Biotechnol. 22, 8-14.

18 Parmley, S. F. and Smith, G. P. (1988) Antibody selectable filamentous fd phage vectors: affinity purification of target genes. Gene 73, 305-318.

19 Hawlisch, H., Müller, M., Frank, R., Bautsch, W., Klos, A., and Köhl, J. (2001) Sitespecific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets. Anal. Biochem. 293, 142-145.

20 Moghaddam, A., Borgen, T., Stacy, J., Kausmally,L., Simonsen, B., Marvik, O. J., et al. (2003) Identification of scFv antibody fragments that specifically recognise the heroin metabolite 6-monoacetyl-morphine but not morphine. J. Immunol. Meth. 280, 139-155.

21 Hust, M., Maiss, E., Jacobsen, H.-J., and Reinard, T. (2002) The production of a genus specific recombinant antibody (scFv) using a recombinant Potyvirus protease. J. Virol. Meth. 106, 225-233.

22 Visintin, M., Tse, E., Axelson, H., Rabbitts, T. H., and Cattaneo, A. (1999) Selection of antibodies for intracellular function using a two-hybrid in vivo system. Proc. Natl. Acad. Sci. USA 96, 11,723-11,728.

23 Biocca, S., Ruberti, F., Tafani, M., Pierandrei-Amaldi, P., and Cattaneo, A. (1995) Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria. Bio/ Technology 13, 1110-1115.

24 Fuchs, P., Breitling, F., Dübel, S., Seehaus, T., and Little, M. (1991) Targeting recombinant antibodies to the surface of E. coli: fusion to a peptidoglycan associated lipoprotein. Bio/Technology 9,1369-1372.

25 Fuchs, P., Weichel, W., Dübel, S., Breitling, F., and Little, M. (1996) Specific selection of E. coli expressing functional cell-wall bound antibody fragments by FACS. Immunotechnology 2, 97-102.

26. Harvey, B. R., Rogers, G. K., Iverson, B. I., and Georgiou, G. (2002) Anchored periplasmic expression (APEx): a new platform for library screening and affinity maturation. Conference book IBC's 13th international conference, Antibody Engineering.

27 Boder, E. T. and Wittrip. K. D. (1997) Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotech. 15, 553-558.

28 Mattheakiss, L. C., Bhatt, R. R., and Dower, W. J. (1994) An in vitro polysome display system for identifying ligands form very large peptide libraries. Proc. Natl. Acad. Sci. USA 91, 9022-9026.

29 Hanes, J. and Plückthun, A. (1997) In vitro selection and evolution of functional proteins by using ribosome display. Proc. Natl. Acad. Sci. USA 94, 4937-4942.

30 Roberts, R. W. and Szostak, J. W. (1997) RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc. Natl. Acad. Sci. USA 94, 12,297-12,302.

31. McCafferty, J., Hoogenboom, H. R., and Chiswell, D. J. (1996) Antibody Engineering: A Practical Approach. Oxford University Press, Oxford, UK.

32. Kontermann, R. E. and Dübel, S. (eds.) (2001) Antibody Engineering. Springer Lab Manuals, Berlin, Germany.

33 Danner, S. and Belasco, J. G. (2001) T7 phage display: A novel genetic selection system for cloning RNA-binding protein from cDNA libraries. Proc. Natl. Acad. Sci. USA 98, 12,954-12,959.

34 Mullinax, R.L, Gross, E. A., Amberg, J. R., Hay, B. N., Hogreffe, H. H., Kubitz, M. M., et al. (1990) Identification of human antibody fragment clones specific for tetanus toxoid in a bacteriophage X immunoexpression library. Proc. Natl. Acad. Sci. USA 87, 8095-8099.

35 Kang, A. S., Jones, T. M., and Burton, D. R. (1991) Antibody redesign by chain shuffling from random combinatorial immunoglobu-lin libraries. Proc. Natl. Acad. Sci. USA 88, 11,120-11,123.

36 Skerra, A. and Plückthun, A. (1988) Assembly of a functional immunoglobulin Fv fragment in Escherichia coli. Science 240, 1038-1041.

37 Marks, J. D., Griffiths, A. D., Malmqvist, M., Clackson, T. P., Bye, J. M., and Winter, G. (1992) By-passing immunization: building high affinity human antibodies by chain shuffling. Bio/Technology 10, 779-783.

38 Griffiths, A. D., Williams, S. C., Hartley, O., Tomlinson, I. M., Waterhouse, P., Crosby, W., et al. (1994) Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13, 3245-3260.

39 Crissman, J. W. and Smith, G. P. (1984) Gene 3 protein of filamentous phages: evidences for a carboxyl-terminal domain with a role in morphogenesis. Virology 132, 445-455.

40 Kang, A. S., Barbas, C. F., Janda, K. D., Bencovic, S. J., and Lerner, R. A. (1991a) Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. Proc. Natl. Acad. Sci. USA 88, 4363-4366.

41 Cwirla, S. E., Peters, E. A., Barrett, R. W., and Dower, W. J. (1990) Peptides on phage: a vast library of peptides for identifying ligands. Proc. Natl. Acad. Sci. USA 87, 6378-6382.

42 Felici, F., Castagnoli, L., Musacchio, A., Jappelli, R., and Cesareni, G. (1991) Selection of antibody ligands from a large library of oligopeptides expressed on a multivalent exposition vector. J. Mol. Biol. 222, 301-310.

43 Jespers, L. S., Messens, J. H., de Keyser, A., Eeckhout, D., van den Brande, I., Gansemans, Y. G., et al. (1995) Surface expression and ligand based selection of cDNAs fused to filamentous phage gene VI. Bio/Technology 13, 378-381.

44 Gao, C., Mao, S., Lo, C. H., Wirsching, P., Lerner, R. A., and Janda, K. D. (1999) Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays. Proc. Natl. Acad. Sci. USA 96, 6025-30.

45 Vieira, J. and Messing, J. (1987) Production of single-stranded plas-mid DNA. Methods Enzymol. 153, 3-11.

46. O'Connel, D., Becerril, B., Roy-Burman, A., Daws, M., and Marks, J. D. (2002) Phage versus phagemid libraries for generation of human monoclonal antibodies. J. Mol. Biol. 321, 49-56.

47 Garrard, L. J., Yang, M., O'Connel, M. P., Kelley, R., and Henner, D. J. (1991) Fab assembly and enrichment in a monovalent phage display system. Bio/Technology 9, 1373-1377.

48 Lowman, H. B., Bass, S. H., Simpson, N., and Wells, J. A. (1991) Selecting High-Affinity binding proteins by monovalent phage display. Biochemistry 30, 10,832-10,838.

49 Rondot, S., Koch, J., Breitling, F., and Dübel, S. (2001) A helperphage to improve single chain antibody presentation in phage display. Nat. Biotechnol. 19, 75-78.

50 Baek, H., Suk, K. H., Kim, Y. H., and Cha, S. (2002) An improved helper phage system for efficient isolation of specific antibody molecules in phage display. Nucleic Acids Res. 30, e18.

51 Spada, S. and Plückthun, A. (1997) Selectivity infective phage (SIP) technology: A novel method for in vivo selection of interacting pro-tein-ligand pairs. Nat. Med. 3, 694-696.

52 Paschke, M., Zahn, G., Warsinke, A., and Höhne, W. (2001) New series of vectors for phage display and prokaryotic expression of proteins. BioTechniques 30, 720-726.

53 Jacob, F. and Monod J. (1961) Genetic regulatory mechanism in the synthesis of proteins. J. Mol. Biol. 3, 318-356.

54 Zahn, G., Skerra, A., and Höhne, W. (1999) Investigation of a tetracycline-regulated phage display system. Protein Eng. 12, 1031-1034.

55 Bujard, H., Gentz, R., Lanzer, M., Stueber, D., Mueller, M., Ibrahimi, I., et al. (1987) A T5 promoter-based transcription-translation system for the analysis of proteins in vitro and in vivo. Methods Enzymol. 155, 416-433.

56 Lei, S.-P., Lin, H.-C, Wang, S.-S., Callaway, J., and Wilcox, G. (1987) Characterization of the Erwinia caratovorapelB gene and its product pectate lyase. J. Bacteriol. 169, 4379-4383.

57 Skerra, A., Pfitzinger, I., and Plückthun, A. (1993) The functional expression of antibody Fv fragments in Escherichia coli: improved vectors and a generally applicable purification technique. Bio/Technology 9, 273-278.

58 Skerra, A. and Schmidt, T. G. M. (1999) Applications of a peptide ligand for streptavidin: the Strep-tag. Biomol. Engineer. 16, 79-86.

59 McCafferty, J., Fitzgerald, K. J., Earnshaw, J., Chiswell, D. J., Link, J., Smith, R., and Kenten, J. (1994) Selection and rapid purification of murine antibody fragments that bind a transition-state analog by phage-display. Appl. Biochem. Biotech. 47, 157-173.

60 Simmons, L. C., Reilly, D., Klimowski, L., Raju, T. S., Meng, G., Sims, P., et al. (2002) Expression of full-length immunoglobulins in Escherichia coli: rapid and efficient production of aglycosylated antibodies. J. Immunol. Methods 263, 133-147.

61 Bird, R. E., Hardman, K. D., Jacobsen, J. W., Johnson, S., Kaufman, B.M, Lee, S. M., et al. (1988) Single-chain antigen-binding proteins. Science 242, 423-426.

62 Bird, R. E. and Walker, B. W. (1991) Single chain variable regions. Trends Biotech. 9, 132-137.

63 Huston, J. S., Levinson, D., Mudgett, H. M., Tai, M. S., Novotny, J., Margolies, M. N., et al. (1988) Protein engineering of antibody binding sites: recovery of specific activity in an anti-digosin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 85,5879-5883.

64 Kortt, A. A., Lah, M., Oddie, G. W., Gruen, L. C., Burns, J. E., Pearce, L. A., et al. (1997) Single chain Fv fragments of anti-neurominidase antibody NC10 containing five and ten residue link ers form dimers and with zero residue linker a trimer. Prot. Eng. 10, 423-428.

65 Arndt, K. M., Müller, K. M., and Plückthun, A. (1998) Factors influencing the dimer to monomer transition of an antibody single-chain Fv fragment. Biochemistry 37, 12,918-12,926.

66 Le Gall, F., Kipriyanov, S. M., Moldenhauer, G., and Little, M. (1999) Di-, tri- and tetrameric single chain Fv antibody fragments against human CD19: effect of valency on cell binding. FEBS Lett. 453, 164-168.

67 Marks, J. D., Hoogenboom, H. R., Griffiths, A. D., and Winter, G. (1992) Molecular evolution of proteins on filamentous phage. J. Biol. Chem. 267, 16,007-16,010.

68 Iliades, P., Dougan, D. A., Oddie, G. W., Metzger, D. W., Hudson, P. J., and Kortt, A. A. (1998) Single-chain Fv of anti-idiotype 11-1G10 antibody interacts with antibody NC41 single-chain Fv with a higher affinity than the affinity for the interaction of the parent Fab fragments. J. Protein. Chem. 17, 245-254.

69. Plückthun, A. (1990) Antibodies from Escherichia coli. Nature 347, 497-498.

70. Plückthun, A. (1991) Antibody engineering: advances from the use of Escherichia coli expression systems. Bio/Technology 9, 545-551.

71 Kramer, K., Fiedler, M., Skerra, A., and Hock, B. (2002) A generic strategy for subcloning antibody variable regions from the scFv phage display vector pCANTAB 5 E into pASK85 permits the economical production of Fab fragments and leads to improved recombinant immunoglobulin stability. Biosensors Bioelectronics 17,305-313.

72 Ward, E. S. (1993) Antibody engineering using Escherichia coli as host. Adv. Pharmacol. 24, 1-20.

73 De Haardt, H. J., van Neer, N., Reurst, A., Hufton, S. E., Roovers, R. C., Henderikx, P., et al. (1999) A large non-immunized human fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies. J. Biol. Chem. 274, 18,218-18,230.

74 Welschof, M., Terness, P., Kipriyanov, S., Stanescu, D., Breitling, F., Dorsam, H., et al. (1997) The antigen binding domain of a human

IgG-anti-F(ab')2 autoantibody. Proc. Natl. Acad. Sci. USA 94, 1902-1907.

75. Dübel, S., Breitling, F., Fuchs, P., Braunagel, M., Klewinghaus, I., and Little, M. (1993) A family of vectors for surface display and production of antibodies. Gene 128, 97-101.

76 Schmiedl, A., Breitling, F., and Dübel, S. (2000) Expression of a bispecific dsFv-dsFv' antibody fragment in Escherichia coli. Protein Eng. 13, 725-734.

77 Iba, Y., Ito, W., and Kurosawa, Y. (1997) Expression vectors for the introduction of higly diverged sequences into the six complementarity-determining regions of an antibody. Gene 194, 35-46.

78 Krebber, A., Bornhauser, S., Burmester, J., Honegger, A., Willuda, J., Bosshard, H. R., and Plückthun, A. (1997) Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system. J. Immunol. Meth. 201, 35-55.

79 Haidaris, C. G., Malone, J., Sherrill, L. A., Bliss, J. M., Gaspari, A. A., Insel, R. A., et al. (2001) Recombinant human antibody single chain variable fragments reactive with Candida albicans surface antigens. J. Immunol. Meth. 257, 185-202.

80. Barbas III, C. F., Burton, D. R., Scott, J. K., and Silverman G. J. (2001) Phage Display: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.

81 Tsurushita, N., Fu, H., and Warren, C. (1996) Phage display vectors for in vivo recombination of immunoglobulin heavy and light chain genes to make large combinatorial libraries. Gene 172, 59-63.

82 Pini, A, Viti, F., Santucci, A., Carnemolla, B., Zardi, L., Neri, P., and Neri, D. (1998) Design and use of a phage display library. J. Biol. Chem. 273, 21,769-21,776.

83 Viti, F., Nilsson, V., Demartis, S., Huber, A., and Neri, D. (2000) Design and use of phage display libraries for the selection of antibodies and enzymes. Meth. Enzymol. 326, 480-497.

84. Söderlind, E., Lagerkvist, A. C.S., Duenas, M., Malmborg, A.-C., Ayala, M., Danielsson, L., and Borrebaeck, C. A. K. (1993) Chaperonin assisted phage display of antibody fragments of filamentous bacteriophages. Bio/Technology 11, 503-507.

85 Kobayashi, N. Söderlind, E., and Borrebaeck, C. A. K. (1997) Analysis of assembly of synthetic antibody fragments: Expression of functional scFv with predifined specificity. BioTechniques 23, 500-503.

86 Jirholt, P., Ohlin, M., Borrebaeck, C. A. K., and Soderlind (1998) Exploiting sequences space: shuffling in vivo formed complementarity determining regions into a master framework. Gene 215,471-476.

87. 0rum, H., Andersen, P. S., 0ster, A., Johansen, L. K., Riise, E., Bj0rnevad, M., et al. (1993) Efficient method for constructing comprehensive murine Fab antibody libraries displayed on phage. Nucl. Acids Res. 21, 4491-4498.

88 Dziegiel, M., Nielsen, L. K., Andersen, P. S., Blancher, A., Dickmeiss, E., and Engberg, J. (1995) Phage display used for gene cloning of human recombinant antibody against the erythrocyte surface antigen, rhesus D. J. Immunol. Meth. 182, 7-19.

89. Soderlind, E., Strandberg, L., Jirholt, P., Kobayashi, N., Alexeiva, V., Aberg, A.-M., et al. (2000) Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries. Nat. Biotech. 18, 852-856.

90 Johansen, L. K., Albrechtsen, B., Andersen, H. W., and Engberg, J. (1995) pFab60: a new, efficient vector for expression of antibody Fab fragments displayed on phage. Protein Eng. 8, 1063-1067.

91 Engberg, J. Andersen, P. S., Nielsen, L. K., Dziegiel, M., Johansen, L. K., and Albrechtsen, B. (1996) Phage-display libraries of murine and human Fab fragments. Mol. Biotechnol. 6, 287-310.

92 Hoogenboom, H. R. and Winter, G. (1992) By-passing immunisation: Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro. J. Mol. Biol. 227, 381-388.

93 Finnern, R., Pedrollo, E., Fisch, I., Wieslander, J., Marks, J. D., Lockwood, C. M., and Ouwehand, W. H. (1997) Human autoimmune anti-proteinase 3 scFv from a phage display library. Clin. Exp. Immunol. 107, 269-81.

94 Rojas, Gertrudis, Almagro, J. C., Acevedo, B., and Gavilondo, J. V. (2002) Phage antibody fragments library combining a single human light chain variable region with immune mouse heavy chain variable regions. J. Biotech. 94, 287-298.

95 Den, W., Sompuram, S. R., Sarantopoulos, S., and Sharon, J. (1999) A bidirectional phage display vector for the selection and mass transfer of polyclonal antibody libraries. J. Immunol. Meth. 222, 45-57.

96. Ge, L., Knappik, A., Pack, P., Freund, C., and Pluckthun, A. (1995) Expressing antibodies in Escherichia coli, in Antibody Engineering (Borrebaeck, C. A. K., ed.), Oxford University Press, Oxford, UK.

97 Goletz, A., Cristensen, P. A., Kristensen, P., Blohm, D., Tomlinson, I., Winter, G., and Karsten, U. (2002) Selection of large diversities of antiidiotypic antibody fragments by phage display. J. Mol. Biol. 315,1087-1097.

98 Garrard, L. J. and Henner, D. J. (1993) Selection of an anti-IGF-1 Fab from a Fab phage library created by mutagenesis of multiple CDR loops. Gene 128, 103-109.

99 Geoffroy, F., Sodoyer, R., and Aujame, L. (1994) A new phage display system to construct multicombinatorial libraries of very large antibody repertoires. Gene 151, 109-113.

100 Knappik, A., Ge, L., Honegger, A., Pack, P., Fischer, M., Wellnhofer, G., et al. (2000) Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus framework and CDRs randomized with trinucleotides. J. Mol. Biol. 296, 57-86.

101 Akamatsu, Y., Cole, M. S., Tso, J. Y., and Tsurushita, N. (1993) Construction of a human Ig combinatorial library from genomic V segments and synthetic CDR3 fragments. J. Immunol. 151, 4651-4659.

102 Vaughan, T. J., Williams, A. J., Pritchard, K., Osbourn, J. K., Pope, A. R., Earnshaw, J. C., et al. (1996) Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat. Biotech. 14, 309-314.

103 Barbas III, C. F., Bain, J.D,, Hoekstra, M., and Lerner, R. A. (1992) Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problems. Proc. Natl. Acad. Sci. USA 89, 4457-4461.

104 Barbas III, C. F., Amberg, W., Simoncsitis, A., Jones, T. M., and Lerner, R. A. (1993) Selection of human anti-hapten antibodies from semisynthetic libraries. Gene 137, 57-62.

105 Desiderio, A., Franconi, R., Lopez, M., Villani, A. E., Viti, F., Chiaraluce, R., et al. (2001) A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold. J. Mol. Biol. 310, 603-615.

106 Sheets, M. D., Amersdorfer, P., Finnern, R., Sargent, P., Lindqvist, E., Schier, R., et al. (1998) Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proc. Natl. Acad. Sci. USA 95, 6157-6162.

107 Nissim, A., Hoogenboom, H. R., Tomlinson, I. M., Flynn, G., Midgley, C., Lane, D., et al. (1994) Antibody fragments from a

"single pot" phage display library as immunochemical reagents. EMBO J. 13, 692-698.

108 De Kruif, J. Boel, E., and Logtenberg, T. (1995) Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions. J. Mol. Biol. 248, 97-105.

109. Dörsam, H., Rohrbach, P, Kürschner, T. Kipriyanov, S., Renner, S., Braunnagel, M., et al. (1997) Antibodies to steroids from a small human naive IgM library. FEBS Lett. 414, 7-13.

110. Little, M., Welschof, M., Braunagel, M., Hermes, I., Christ, C., Keller, A., et al. (1999) Generation of a large complex antibody library from multiple donors. J. Immunol. Meth. 231, 3-9.

111. Schmidt, A., Müller, D., Mersmann, M., Wüest, T., Gerlach, E., Garin-Chesa, P., et al. (2001) Generation of human high-affinity antibodies specific for the fibroblast activation protein by guided selection. Eur. J. Biochem. 268, 1730-1738.

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