Michael Hust and Stefan Dbel

Summary

A major source of human antibodies are phage display libraries, which are constructed from various genetic sources. Antibodies are expressed as scFV and Fab antibody fragments using various vector systems. This review offers a comprehensive overview of M13 ph-age display antibody vectors and discusses their applications.

Key Words: Antibody (Ab); fragment antigen binding (Fab); fragment variable (Fv); single-chain Fv (scFv); variable part of heavy chain; variable part of light chain; wild type.

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