The Asthmatic Patient

Patient Mechanical Ventilation

Acute changes in lung mechanics experienced by patients with severe bron-chospasm due to asthma attacks are similar to those observed in COPD during acute exacerbations. However, the pathophysiology of asthma may differ substantially from that of COPD. Increased airway collapsibility due to destruction of the lung parenchyma and loss of lung elastic recoil is a main feature of COPD patients. In asthma, the increases inbronchomotortone, and inflammatory infiltration may Fig. 4. Same patient as...

Cardiovascular Effects

Picture Mechanical Ventilator Aprv

When cardiac function is normal, the filling of the right and left ventricle during diastole is the predominant determinant of the stroke volume and cardiac output. Positive pressure ventilation increases intrathoracic pressure, which in turn reduces the venous return to the heart 34 . In normo- and hypovolemic patients, this produces reduction in right- and left-ventricular filling and results in decreased stroke volume, cardiac output and oxygen delivery DO2 . To normalize systemic blood flow...