All three lymph nodes were free of disease by H&E and immunohistochemistry staining (HMB-45, S-100). Six months later, the patient came to the clinic because he felt a lump in the neck. A 1-cm rubbery node was palpated in the right supraclavicular fossa. Fine-needle aspiration cytology revealed melanoma cells. A radical right neck dissection was performed after a search for other sites of disease (including computed tomography scans of chest, neck, and brain; liver ultrasound; bone scintigraphy; blood chemistry) revealed no other tumor locations. Two supraclavicular nodes contained melanoma deposits; the other 28 nodes in the specimen were free of disease. A distant skin metastasis was discovered 9 months later. The patient died from brain metastases 1 year after the neck dissection.
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Complete Guide to Preventing Skin Cancer. We all know enough to fear the name, just as we do the words tumor and malignant. But apart from that, most of us know very little at all about cancer, especially skin cancer in itself. If I were to ask you to tell me about skin cancer right now, what would you say? Apart from the fact that its a cancer on the skin, that is.