Studies appeared describing the use of an intraoperative gamma probe to locate sentinel lymph nodes during surgery [36-38]. Most now accept that the best method of locating the sentinel nodes at surgery is to use a combination of preop-erative lymphoscintigraphy, blue dye injection just before anesthesia, and intraoperative use of a gamma probe to assist in locating the blue node or nodes and show that the node field returns to background levels of activity after the sentinel nodes are removed [39,40]. The delay between the injection of tracer and surgery will vary with different protocols; however, there is enough radioactivity remaining in the sentinel nodes to allow the gamma probe to be used up to 24 h after injection of the tracer. In fact, there are some advantages in this next-day surgical approach. There is less radiation safety concern for operating theater staff and no requirement for radiation licensing of the surgeon. Further, the node-to-background ratio rises with time, which facilitates the location of ''hot'' nodes using the gamma detection probe intraoperatively .
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Complete Guide to Preventing Skin Cancer. We all know enough to fear the name, just as we do the words tumor and malignant. But apart from that, most of us know very little at all about cancer, especially skin cancer in itself. If I were to ask you to tell me about skin cancer right now, what would you say? Apart from the fact that its a cancer on the skin, that is.