Index

Chemo Secrets From a Breast Cancer Survivor

Breast Cancer Survivors

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Aas, 191

Adjuvant therapy, 88, 102, 117, 141, 148, 153, 168, 177, 339, 342, 361, 364 Albumin,

99mTc-colloid, 31, 102, 106, 115, 173 99mTc-labeled human serum, 47, 48, 102, 106, 108, 115, 362 Allergic reaction, 46, 62, 75 Antibody, 34, 63, 168, 245, 249, 360, 364

Antimony trisulfide colloid, 31, 47, 48, 158, 161, 220, 362

Arm, 8 Aselli, 23

Bartholin, 23 Bladder, 36 Blood, 151

Blue dye, 24, 73, 76, 115, 116, 169, 192, 205, 209, 274 allergic reaction, 75 injection technique, 74, 104, 172,

205, 329 lymphangiography, 29 side effects, 75, 318

Bone, 267

scintigraphy, 269 Bowel, 36

see also Intestine Breast, bone metastasis, 268 cancer, excised, 161, 172 in situ, 175

lymphoscintigraphy, 33, 157, 174,

231, 322, 336 multicentric, 179 nonpalpable, 161 sentinel node biopsy, 34, 168, 362

lymphatic drainage, 11, 32, 362

Cabanas, 28, 35, 204, 205, 208, 364 Carcinoembryonic antigen, 250, 256 Cervical cancer, 352 Chondroma, 280 Cisterna chyli, 6 Cloquet, 54, 290, 315 Cobalt-57, 87

flood source, 50, 286 Cochran, 28, 105

Colloid, 24, 47 albumin, 31, 102, 106, 115, 173, 362 antimony trisulfide, 31, 47, 48, 158,

nanocolloid, 48, 192, 205, 218, 362

particles, 24, 47, 63

volume, 47, 162, 163 Colorectal cancer, 245, 365

see also Bowel, intestine large Computed tomography, 43, 64, 102, 168, 191, 204, 250, 271, 360, 364

Cost, 110-112 Cruikshank, 23

Daseler, 203

Diphosphonate-99mTc, 269 DiSaia, 191

Ductal carcinoma in situ, 175 Dye (see Blue dye)

Edema, 44, 77, 167, 188, 204, 318 Ege, 32 Eichner, 24

Endometrial cancer, 36, 352

Fee, 25 Fisher, 167

Flood source, cobalt-57, 50, 286 Foot, 8, 107 Frozen section, in breast cancer, 170, 174, 330 in hyperparathyroidism, 241 in melanoma, 77, 127, 170, 174

Gabelle, 33 Galen, 23

306 Gasparini, 33

Gastrointestinal (see Bowel, intestine) Gerota, 24

Haagensen, 25, 168 Halsted, 167 Hand, 8

Hewson, 23

HMB-45, 126-133, 135 Hultborn, 157

Imaging, delayed, 163 dynamic, 29, 48, 49, 205

see also Immediate flow (see Dynamic) gamma camera, 29, 44, 49, 161 immediate, 162

see also Dynamic late (see Static) static, 48, 49, 205

see also Delayed technique, 48, 162, 323 see also Lymphoscintigraphy Immunohistochemistry, in breast cancer, 170, 175, 231, 331, 343

in colorectal cancer, 246, 259 in melanoma, 105, 117, 126, 129,

143, 150, 228 in penile cancer, 206, 209 Injection, into the breast, 34, 329, 339, 362 intradermal, 20

in melanoma, 46, 74, 104, 220 in breast cancer, 34, 329, 339 in penile cancer, 205 intratumoral, 33, 103, 348, 362 periareolar, 33 periost, 274

218, 362 subareolar, 33, 339

[Injection] subcutaneous 46, 220, 362 subperiostal, 33

technique, 45, 74, 102, 162, 172, 362 volume, 47, 158, 162, 172, 363 Interferon-a, 117, 141, 153, 361 Internal mammary lymphoscintigraphy,

32, 33, 157, 160, 337, 341 Intestine, large, 9, 36, 232, 268

see also Bowel, colorectal small, 8, 232 Iodine-125, 246 Iversen, 191

Kidney, 8, 23, 268 Kinmoth, 23

Lacteal, 8

Learning phase, 117, 196, 227, 230, 320, 321, 326, 334, 350 see also Learning curve Leg, 8, 53

Liver metastasis, 255 Lung, 10, 268, 277

see also Pulmonary Lymph, composition, 18

flow, 1, 3, 8, 15, 47, 49, 72, 205 formation, 12 physiology, 1 propulsion, 15 Lymphadenectomy see Lymph node dissection Lymphangiography, 24, 29, 35, 43, 44,

157, 204, 208 Lymphangioma, 60 Lymphangion, 5, 15, 16 Lymphatic, anatomy, 2 capillaries, 2, 3, 31

see also Initial channel, 49

collecting vessel, 2, 5, 10

[Lymphatic] collector (see Collecting vessel) conducting (see Collecting vessel) drainage, breast, 11, 32, 362 intestine, 8, 9 kidney, 8 lung, 10 neck, 52

penis, 10, 204, 208 reproductive organs, 10 skin, 7, 24, 31 unexpected, 31 vulva, 191 epidermal, 7 initial, 2-5

see also Lymphatic capillaries intraluminal pressure, 4-6, 17 lake, 60, 78, 295, 304 microanatomy, 2 obstruction, 6 plexus, breast, 11 kidney, 8 large intestine, 9 subareolar, 11, 339 testis, 10

thoracic surface, 11 prelymphatics (see Initial lymphatics) subdermal, 7 system, 1 terminal, 2 valve, 5 Lymphedema (see Edema) Lymph node, axillary, 11

breast parenchyma, 346 Cloquet's, 54, 290, 315 culture, 144

dissection complications, 167, 188, 204 dissection elective in breast cancer, 34, 167

dissection elective in melanoma, 101, 125

dissection elective in penile cancer, 203, 204, 210, 357

[Lymph node] dissection elective in vulvar cancer,

187, 189, 351 dissection therapeutic in melanoma,

315, 359 epitrochlear, 303 groin, 53, 315

see also Inguinal hypogastric, 54 iliac, 10, 36, 54, 204 infraclavicular, 11, 160, 335 inguinal, 10, 107 see also Groin intercostal, 11

internal mammary, 11, 157, 158, 160,

163, 178, 323, 337, 341, 349 lymph flow in, 17 mediastinal, 11 neck, 107 para-aortic, 36

parasternal (see Internal mammary)

pectoral, 11

pelvis, 36, 189, 204

popliteal, 302

rectal, 10

Rotter's, 11, 345

sacral, 10

subclavicular, 335

subscapular, 11

supraclavicular, 11, 158, 160, 163, 349

Lymphoma, 277

Lymphoscintigraphy, 24, 43, 72, 362 axillary, 33 complications, 62

groin, 209, 210 internal mammary, 32, 157 mammary, 33, 157, 174, 231, 322, 336 reproducibility, 54, 299, 362 see also Imaging

McBride, 25

Magnetic resonance imaging, 43, 64, 102, 168, 191, 204, 271, 360, 364

Mammography, 161, 168, 172

205, 320 Martin, 246 Massa, 23

327 Matsubara, 34 Mazzeo, 33 Melanoma, adjuvant therapy, 102, 117, 141, 148,

153, 361 bone metastasis, 277 injection technique, 45, 74 in transit metastases, 360 lymphoscintigraphy, 43, 72 results of lymphatic mapping in, 101 sentinel node biopsy technique, 71, 102

Merkel's cell tumor, 32, 44, 232, 352 Meyers, 246

Morton, 28, 29, 34, 45, 74, 77, 102, 105-108, 114, 115, 117, 143, 168, 194, 205, 208, 226, 233, 360

Multicenter selective lymphadenectomy trial, 127, 134, 227, 292, 360

Nanocolloid, 48, 192, 205, 218, 362

uptake, 54 Neck (see Head and neck)

Oxidronate-99mTc, 275

Pancreas, 232, 263 Parathyroid gland, 235, 269 Particles, shape, 63

size, 24, 31, 47, 161, 163 surface, 63 characteristics, 63 Pathology, cytology, 360

frozen sections, 77, 127, 170, 174, 241, 330

hematoxylin & eosin, 105, 117, 143, 150, 174, 206, 228, 232, 246, 259

[Pathology]

immunohistochemistry, 105, 117, 126, 129, 143, 150, 170, 175, 206, 209, 228, 231, 246, 259, 343

lymph node culture, 144 micrometastasis, 143, 146, 150, 175, 176

246, 308, 361 serial sectioning, 128, 129, 136, 143,

209, 228, 231, 259 step sectioning (see Serial sectioning) technique, 128

touch prep cytology, 174, 331 Pelvis, 255

Penis, 10, 28, 35, 189, 203, 356, 364 PET (see Positron emission tomography)

Positron emission tomography, 64, 102,

168, 191, 316, 360, 364 Probe, gamma ray detection, 87 characteristics, 88-90 collimation, 248 collimator, 89-99, 277, 347 control unit, 98 crystal characteristics, 88 energy resolution, 80 energy threshold, 95 intraoperative use, 31, 79-82, 108, 116, 158, 174, 192, 206, 209, 236, 246, 329 intrinsic detector efficiency, 88 maintenance, 98 safety, 98 selection, 99

sensitivity, 89-93, 95, 347 shape, 97

spatial resolution, 89, 92 weight, 97 Prostate, 36, 268, 277 Pulmonary, 10, 365

Radiation dose, 62, 213-222 see also Radiation risk

Radiation protection, 214 Radiation risk, 133, 214

see also Radiation dose Radioguided bone biopsy, 267 Radioguided parathyroidectomy, 235 Radioimmunoguided surgery, 245 Radiopharmaceutical, 31, 47, 116, 173, 269, 363

albumin-99mTc colloid, 31, 102, 106, 115

albumin-99mTc human serum, 47, 48,

102, 106, 108, 115, 173, 362 allergic reaction, 46, 62 antibody, 34, 63, 168, 245, 249, 360

antimony trisulfide colloid, 31, 47,

48, 158, 161, 220, 362 colloid gold, 24, 25, 32, 158 complications, 62 dextran, 173

diphosphonate-99mTc, 269 dose, 46

nanocolloid, 48, 192, 205, 218, 362 oxidronate-99mTc, 275 sestamibi-99mTc, 235, 364 sulfur colloid, 31, 47, 48, 102, 106,

volume, 47, 158, 162, 163, 363 Randomized trial, 117, 127, 162, 178,

227, 360, 363 Rectum (see Intestine large) Regional lymph node dissection, complications, 167, 188, 204 elective in breast cancer, 34, 167 elective in melanoma, 101, 125 elective in penile cancer, 203, 204, 210, 357

elective in vulvar cancer, 187, 189, 351

therapeutic in melanoma, 315, 359 Reproductive organs, 10 endometrium, 36, 352 uterus, 36

Reverse transcriptase-polymerase chain reaction, in blood, 151 in breast cancer, 178 in colorectal cancer, 246 in melanoma, 117, 136, 145-153,

308, 361 technique, 145 Rodgers, 154 Rossi, 32 Rotter, 11, 345 Rouviere, 203

RT-PCR (see Reverse transcriptase-poly-

merase chain reaction) Rudbeck, 23

Sappey, 23-28, 292 subareolar plexus, 11 line, 24, 57 Sarcoma, 268, 354

Scattered radiation, 95, 248, 312, 345,

347, 348 Schenck, 32 Selverstone, 213 Sentinel lymph node, concept, 28, 168, 308 definition, 45, 174, 205, 289, 292 extra-anatomic, 58

see also Interval sentinel lymph node, in transit sentinel lymph node interval, 29, 58, 304

see also Extra-anatomic sentinel lymph node, in transit sentinel lymph node in transit, 57, 78

see also Extra-anatomic sentinel lymph node, interval sentinel lymph node) Sentinel node biopsy, complications, 112, 177, 191, 208, 317 cost, 110-112

survival after, 113, 360, 363 technique, 71, 102, 172, 192, 205, 325, 329, 361

Serial sectioning, 128, 129, 136, 143, 228, 231, 259 see also Step sectioning Serin, 33

Sestamibi-99mTc, 235, 364 Sherman, 24 Skin, 7, 24, 31 Snow, 101

Squamous cell carcinoma, 32, 44, 186,

203, 232, 350, 354, 356 Stage migration, 154 Step sectioning, 209

see also Serial sectioning Sugarbaker, 25

Sulfur colloid, 31, 47, 48, 102, 106, 108, 115, 158, 161, 173, 362 Sunbelt melanoma trial, 117, 149, 153 Survival, 113, 142, 146, 339, 360, 363

334, 362 Terui, 33 Thigh, 8 Thurston, 246 Thyroid cancer, 232, 268 Thoracic duct, 3, 5, 6, 17 Touch prep cytology, 174, 331 Trunk, 8

172, 191, 204, 360, 364 Uterine cancer, 36

Vendrell-Torne, 32, 158 Vital dye (see Blue dye) Von Pecquet, 23

Walker, 24 Wayne, John,

Cancer Institute, 28, 114, 117 gunslinger, 393 Weinberg, 24

Yamamoto, 33

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