Role of Cholesterol in Signal Transduction from Caveolae

Christopher J. Fielding and Phoebe E. Fielding

5.1 Introduction 91

5.2 Lipids of Caveolae 93

5.3 Proteins in Caveolae 95

5.4 The Caveolin Scaffold Hypothesis 98

5.4.1 Does the Scaffold Motif in Signaling Proteins that are Present in Caveolae Represent the Contact Site of these Proteins with Caveolin? 99

5.5 FC Binding by Proteins Including Caveolin 101

5.6 FC in Caveolae: Effects of Depletion and Loading 102

5.7 FC Changes in Caveolae: Effects of Signal Transduction 104

5.8 Summary 107 Abbreviations 107 References 107

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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