Lipid Rafts Caveolae and Membrane Traffic

Doris Meder and Kai Simons

1.1 Introduction 1

1.2 Basic Organization Principles of a Cell Membrane 1

1.3 Evidence for Phase Separation in Model Membrane Systems: Liquid-Ordered and Liquid-Disordered Phases 3

1.4 Evidence for Phase Separation in Cell Membranes: The "Raft Concept" 5

1.5 Raft Domains are Clustered to Exert their Function S

1.6 The Apical Membrane of Epithelial Cells: A Percolating Raft Membrane at 25 °C 9

1.7 Caveolae: Scaffolded Membrane Domains Rich in Raft Lipids 10

1.8 Caveolae and Lipid Rafts in Membrane Traffic 12 Abbreviations 17

References 17

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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