Glycerolipids are the most widespread of membrane lipids. Phosphoglycerides dominate in higher animals whereas glycosylglycerides are important in plants.

Three important classes of membrane lipid are widely distributed - glycerolipids, sphingolipids and steroids. Of these, glycerolipids are quantitatively by far the most important group. They can be conveniently divided into two main groups - those containing phosphorus (phosphoglycerides) and those without phosphorus but containing a sugar constituent (glycosylglycerides). Confusingly, some compounds (e.g. sphingomyelin) can be classified in more than one group.

6.2.1 Phosphoglycerides are the major lipid components of most biological membranes

The stereochemistry of phosphoglycerides was discussed in Chapter 1. The phosphoglycerides comprise a very widespread and diverse group of structures. In most membranes they are the main lipid components and, indeed, the only general exceptions to this statement are the photosynthetic membranes of plants, algae and cyanobacteria and the archaebacterial membranes.

Usually, phosphoglycerides contain fatty acids esterified at positions 1 and 2 of glycerol. They are, thus, diacylphosphoglycerides. These lipids are named after the moiety which is attached to the phosphate esterified at position 3 of glycerol. Thus, the compounds can be thought of as derivatives of diacylglycerols in which the hydroxyl on carbon atom 3 is esterified with phosphoric acid, which in turn is esterified with a range of molecules -organic bases, amino acids, alcohols.

The simplest phosphoglyceride contains only phosphoric acid attached to diacylglycerol and is called phosphatidic acid (Table 6.3). Where addi-

Table 6.3 Structural variety of different diacylglycerophospholipids

Name of phospholipid Source


Was this article helpful?

0 0
Get The Body Of Your Dreams

Get The Body Of Your Dreams

Everybody wants to lose weight. This is one fact that is supported by the countless weight loss programs on the market along with the numerous weight loss products, ranging from snack bars, powdered juices, shakes and even slimming soaps and lotions.

Get My Free Ebook

Post a comment