Stressactivated protein kinase signalling pathways

Type 2 Diabetes Defeated

Holistic Treatment to Reverse Diabetes

Get Instant Access

The principle of a signal transduction pathway was introduced in Chapter 5. An extensively discussed system in that chapter was the insulin/IGF receptor, which proved to be associated with the regulation of longevity in various animals. The insulin-signalling pathway relays a hormonal signal into a cellular response, via a cascade of molecular interactions, eventually leading to inac-tivation of a transcription factor. We saw the same principle in the TOR and Ras pathways acting upon body size in insects and in the phytochrome signalling pathway regulating shade avoidance in plants. The principle of signal transduction is also employed in one of the most elaborate stress-responsive systems, the mitogen-activated

Table 6.1 Overview of stress-related transcription factors and consensus sequences of their DNA binding sites (http:www.gene-regulation.com/ pub/databases.html)

Transcription

DNA-binding site

Consensus sequence

Context

factor

Was this article helpful?

0 0
Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

Get My Free Ebook


Post a comment