Neuroimaging studies

Neuroimaging studies are extremely useful in defining the extent of leptomeningeal disease in children who have underlying primary CNS or solid tumors. Neuroimaging studies also facilitate the identification of areas of bulky disease and the assessment of CSF flow dynamics. In children with CNS leukemia, neuroimaging studies of the brain and/or spinal cord are sometimes obtained if there are focal neurological symptoms (e.g. cranial nerve palsies, visual problems, or localized pain). Furthermore, it is not unreasonable to obtain a baseline head MRI at the initial diagnosis of CNS leukemia or lymphoma.

As with CSF cytology, negative imaging studies do not preclude a diagnosis of leptomeningeal metastases. It has been suggested that if there is a strong clinical suspicion of neoplastic meningitis in the presence of negative cytology and neuroimaging studies, that obtaining a high-dose gadolinium-enhanced MRI may increase the diagnostic yield.18

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook

Post a comment