Patients with diabetes have a markedly greater risk of developing cardiovascular disease and its complications. It is therefore recommended that aspirin therapy be considered for most adult patients who have diabetes. Specifically, it is suggested that aspirin be used as secondary prevention if there is evidence of large-vessel disease (history of myocardial infarction, vascular bypass procedure, stroke, transient ischemic attack, peripheral vascular disease, claudication, or angina). In addition, aspirin should be considered in primary cardiovascular-risk reduction in patients at increased risk for macrovascular disease; so practically most experts recommend aspirin use in all adults with type 2 diabetes. Enteric coated aspirin in doses from 81 to 325 mg per day are suggested.
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