Insulin Glucose Infusion

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Long-term mortality in diabetic patients who are hospitalized for acute MI may be reduced by an insulin-glucose infusion followed by multidose insulin treatment. In the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study, an infusion of insulin and glucose followed by daily subcutaneous injections of insulin resulted in a 52% reduction in mortality within 1 year after myocardial infarction among patients with DM. This beneficial effect was attributed to improved metabolic control in the presence of an extreme increase in the level of catecholamines in blood and ischemic myocardium that is associated with sudden ischemic episodes. Insulin therapy appeared to beneficially influence acute cardiovascular mortality. A striking reduction in the incidence of fatal reinfarction and left ventricular failure was seen. These results are consistent with favorable effects in reducing mortality among diverse groups of patients treated with a glucose-insulin-potassium infusion in the setting of acute MI.

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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