Important Muscle Ebook

Increase Bench Press Program from Critical Bench

The Critical Bench guide has been developed by Mike Westerdal, who is a bodybuilder and fitness trainer. He has also been coach to hundreds of top athletes, many of whom have seen increases in bench press of up to 40-50 pounds within just few weeks. It does not matter whether you have long arms, wrist pain, sub-par genetics or shoulder pain; you can be rest assured you will get all the benefits of this program. In this program, you will learn about various ways of lifting and specific exercises that you can use to increase your bench press safely and quickly. You will also be able to build 200, 300, or 400 plus lb bench press using the unique approach of the program. More than eighteen thousand people have already benefited by using this method. Read more here...

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The Liver Is Important in Carbohydrate Metabolism

Carbohydrate Metabolism Liver

The liver is extremely important in maintaining an adequate supply of nutrients for cell metabolism and regulating blood glucose concentration Fig. 28.3 . After the ingestion of a meal, the blood glucose increases to a concentration of 120 to 150 mg dL, usually in 1 to 2 hours. Glucose is taken up by hepatocytes by a facilitated carrier-mediated process and is converted to glucose 6-phosphate and then UDP-glucose. UDP-glucose can be used for glycogen synthesis, or glycogenesis. It is generally...

Digestion And Absorption Of Lipids

Docosahexaenoic Acid Molecule

Lipids are a concentrated form of energy. They provide 30 to 40 of the daily caloric intake in the Western diet. Lipids are also essential for normal body functions, as they form part of cellular membranes and are precursors of bile acids, steroid hormones, prostaglandins, and leukotrienes. The human body is capable of synthesizing most of the lipids it requires with the exception of the essential fatty acids linoleic acid C 18 2, an 18-carbon long fatty acid with two double bonds and...

Control of Muscle Tension

The total tension a muscle can develop depends upon two factors 1 the amount of tension developed by each fiber, and 2 the number of fibers contracting at any time. By controlling these two factors, the nervous system controls whole-muscle tension, as well as I. Tension developed by each individual fiber a. Action-potential frequency frequency-tension relation b. Fiber length length-tension relation a. Number of fibers per motor unit b. Number of active motor units shortening velocity. The...

Length Tension Relationship

Length Tension Relationship

The strength of a muscle's contraction is influenced by a variety of factors. These include the number of fibers within the muscle that are stimulated to contract, the frequency of stimulation, the thickness of each muscle fiber thicker fibers have more myofibrils and thus can exert more power , and the initial length of the muscle fibers when they are at rest. There is an ideal resting length for striated muscle fibers. This is the length at which they can generate maximum force. When the...

The postsynaptic cell sums excitatory and inhibitory input

Postsynaptic Cell Spatial Summation

Individual neurons can decide whether or not to fire an action potential by summing excitatory and inhibitory postsynaptic potentials. This summation ability is the major mechanism by which the nervous system integrates information. Each neuron may receive a thousand or more synaptic inputs, but it has only one output an action potential in a single axon. All the information contained in all the inputs a neuron receives is reduced to the rate at which that neuron generates nerve impulses in its...

Regulation of Stroke Volume

Frank Starling Law

The stroke volume is regulated by three variables 1 the end-diastolic volume EDV , which is the volume of blood in the ventricles at the end of diastole 2 the total peripheral resistance, which is the frictional resistance, or impedance to blood flow, in the arteries and 3 the contractility, or strength, of ventricular contraction. The end-diastolic volume is the amount of blood in the ventricles immediately before they begin to contract. This is a workload imposed on the ventricles prior to...

Amino Acid Metabolism

Nitrogen is ingested primarily as proteins, enters the body as amino acids, and is excreted mainly as urea in the urine. In childhood, the amount of nitrogen excreted may be less than the amount ingested because amino acids are incorporated into proteins during growth. Growing children are thus said to be in a state of positive nitrogen balance. People who are starving or suffering from prolonged wasting diseases, by contrast, are in a state of negative nitrogen balance they excrete more...

Review Questions

DIRECTIONS Each of the numbered items or incomplete statements in this section is followed by answers or by completions of the statement. Select the ONE lettered answer or completion that is the BEST in each case. 1. Which of the following conditions is consistent with a decreased rate of ACTH secretion A Hyperosmolality of the blood C Loss of hypothalamic neurons D Primary adrenal insufficiency E Stress as a result of emotional trauma F Increased PKA activity in corticotrophs 2. Which of the...

Excitation Contraction Coupling

Tropomyosin And Troponin Actin Myosin

Muscle contraction is turned on when sufficient amounts of Ca2 bind to troponin. This occurs when the Ca2 concentration of the sarcoplasm rises above 10-6 molar. In order for muscle relaxation to occur, therefore, the Ca2 concentration of the sar-coplasm must be lowered to below this level. Muscle relaxation is produced by the active transport of Ca2 out of the sarcoplasm into the sarcoplasmic reticulum fig. 12.15 . The sarcoplasmic reticulum is a modified endoplasmic reticulum, consisting of...

Inspiration and Expiration

Human Expiration

Between the bony portions of the rib cage are two layers of intercostal muscles the external intercostal muscles and the internal intercostal muscles fig. 16.14 . Between the costal cartilages, however, there is only one muscle layer, and its fibers are oriented in a manner similar to those of the internal inter-costals. These muscles are therefore called the interchondral part of the internal intercostals. Another name for them is the parasternal intercostals. An unforced, or quiet,...

Insulin and Glucagon Postabsorptive State

Formation Ketone Bodies

The plasma glucose concentration is maintained surprisingly constant during the fasting, or postabsorptive, state because of the secretion of glucose from the liver. This glucose is derived from the processes of glycogenolysis and gluconeogenesis, which are promoted by a high secretion of glucagon coupled with a low secretion of insulin. Glucagon stimulates and insulin suppresses the hydrolysis of liver glycogen, or glycogenolysis. Thus during times of fasting, when glucagon secretion is high...

Collecting Duct Effect of Antidiuretic Hormone ADH

Collecting Tubules And Vasa Recta

As a result of the recycling of salt between the ascending and descending limbs and the recycling of urea between the collecting duct and the loop of Henle, the interstitial fluid is made very hypertonic. The collecting ducts must channel their fluid through this hypertonic environment in order to empty their contents of urine into the calyces. Whereas the fluid surrounding the collecting ducts in the medulla is hypertonic, the fluid that passes into the collecting ducts in the cortex is...

Types of Skeletal Muscle Fibers

Myoglobin Muscle Fibers

All skeletal-muscle fibers do not have the same mechanical and metabolic characteristics. Different types of fibers can be identified on the basis of 1 their maximal velocities of shortening fast and slow fibers and 2 the major pathway used to form ATP oxida-tive and glycolytic fibers. Fast and slow fibers contain myosin isozymes that differ in the maximal rates at which they split ATP, which in turn determine the maximal rate of cross-bridge cycling and hence the fibers' maximal shortening...

Motor Units

Motor Unit Axonal Terminal

In vivo, each muscle fiber receives a single axon terminal from a somatic motor neuron. The motor neuron stimulates the muscle fiber to contract by liberating acetylcholine at the neuromuscu-lar junction described in chapter 7 . The specialized region of the sarcolemma of the muscle fiber at the neuromuscular junction is known as a motor end plate fig. 12.3 . The acetylcholine ACh released by the axon terminals diffuses across the synaptic cleft and binds to ACh receptors in the plasma membrane...

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