Characteristics Of Allergic Patients

When compared with normals, asthmatics have a skewed profile of peripheral blood lymphocytes and clinical symptoms. The number ofCD4 Th2 cells is greatly increased in allergic subjects. However, there is considerable debate about whether this change is a cause or an effect ofasthma. Moreover, the surface of the Th2 cells has a higher density of a low-affinity receptor for IgE (CD23). The low-affinity receptor is a 30-kDa member of the C-type lectin family that includes the selectin adhesion molecules. Most asthmatics have hyperactive airways and respond to low concentrations of carbachol, a potent cholinergic stimulus, with bronchoconstric-tion. All have increased levels of IgE antibody in the serum.

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Dealing With Asthma Naturally

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