So far, Medline lists only a few studies on this filler. These reports are mostly case reports focusing on granulomatous reactions to HEMA (Requena et al. 2001; Waris 2003). The Berlin registry, however, documents patients with granulomatous reactions as well as a patient with ulcerations following treatment with HEMA (Figs. 6.3 and 6.4). In 2001, Begeret-Galley published an overview in which the overall incidence of late side effects and complications (nodules, swelling, and erythema, on average 6 months after injection) based on data from the manufacturer is given as <1.2 per 1000 patients (Bergeret-Galley et al. 2001). As the data from the manufacturer
is based on spontaneous reports, some degree of underreporting is likely.
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.