Regulation of Glomerular Filtration Rate

Vasoconstriction or dilation of afferent arterioles affects the rate of blood flow to the glomerulus, and thus affects the glomerular filtration rate. Changes in the diameter of the afferent arterioles result from both extrinsic regulatory mechanisms (produced by sympathetic nerve innervation), and intrinsic regulatory mechanisms (those within the kidneys, also termed renal autoregulation). These mechanisms are needed to ensure that the GFR will be high enough to allow the kidneys to eliminate wastes and regulate blood pressure, but not so high as to cause excessive water loss.

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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Responses

  • anja brandt
    What are regulatory categories for filtration rate?
    8 years ago
  • sinikka
    What mechanisms regulate filtration rate?
    5 months ago
  • atso
    What are the mechanism that governs the regulation of the glomerular filtration?
    12 days ago

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