Reabsorption of Salt and Water

Most of the salt and water filtered from the blood is returned to the blood through the wall of the proximal tubule. The reabsorption of water occurs by osmosis, in which water follows the transport of NaCl from the tubule into the surrounding capillaries. Most of the water remaining in the filtrate is reabsorbed across the wall of the collecting duct in the renal medulla. This occurs as a result of the high osmotic pressure of the surrounding tissue fluid, which is produced by transport processes in the loop of Henle.

Although about 180 L of glomerular ultrafiltrate are produced each day, the kidneys normally excrete only 1 to 2 L of urine in a 24-hour period. Approximately 99% of the filtrate must thus be returned to the vascular system, while 1% is excreted in the urine. The urine volume, however, varies according to the needs of the body. When a well-hydrated person drinks a liter or more of water, urine production increases to 16 ml per minute (the equivalent of 23 L per day if this were to continue for 24 hours). In severe dehydration, when the body needs to conserve water, only 0.3 ml of urine per minute, or 400 ml per day, are produced. A volume of 400 ml of urine per day is the minimum needed to excrete the metabolic wastes produced by the body; this is called the obligatory water loss. When water in excess of this amount is excreted, the urine becomes increasingly diluted as its volume is increased.

Regardless of the body's state of hydration, it is clear that most of the filtered water must be returned to the vascular system to maintain blood volume and pressure. The return of filtered molecules from the tubules to the blood is called reabsorption (fig. 17.12). It is important to realize that the transport of water always occurs passively by osmosis; there is no such thing as active transport of water. A concentration gradient must thus be created between tubular fluid and blood that favors the osmotic return of water to the vascular system.

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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  • morgan dalrymple
    How is salt and water be reabsorbed in kidney?
    7 years ago

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