Menstrual Cycle

Cyclic changes in the secretion of gonadotropic hormones from the anterior pituitary cause the ovarian changes during a monthly cycle. The ovarian cycle is accompanied by cyclic changes in the secretion of estradiol and progesterone, which interact with the hypothalamus and pituitary to regulate gonadotropin secretion.The cyclic changes in ovarian hormone secretion also cause changes in the endometrium of the uterus during a menstrual cycle.

Humans, apes, and Old-World monkeys have cycles of ovarian activity that repeat at approximately one-month intervals; hence the name menstrual cycle (menstru = monthly). The term menstruation is used to indicate the periodic shedding of the stratum functionale of the endometrium, which becomes thickened prior to menstruation under the stimulation of ovarian steroid hormones. In primates (other than New-World monkeys) this shedding of the endometrium is accompanied by bleeding. There is no bleeding when most other mammals shed their endometrium, and therefore their cycles are not called menstrual cycles.

In human females and other primates that have menstrual cycles, coitus (sexual intercourse) may be permitted at any time of the cycle. Nonprimate female mammals, by contrast, are sexually receptive (in "heat" or "estrus") only at a particular time in their cycles, shortly before or after ovulation. These animals are therefore said to have estrous cycles. Bleeding occurs in some animals (such as dogs and cats) that have estrous cycles shortly before they permit coitus. This bleeding is a result of high estrogen secretion and is not associated with shedding of the endometrium. The bleeding that accompanies menstruation, by contrast, is caused by a fall in estrogen and progesterone secretion.

Growing Mature primary Primary Secondary (graafian) follicle oocyte follicle follicle Antrum

Corpus albicans

Germinal epithelium

Corpus luteum

Cumulus oophorous

Secondary oocyte

Physiology Oocyte Development

Cumulus oophorous

Corona radiata

Secondary oocyte

Zona pellucida

■ Figure 20.33 Stages of ovum and follicle development. This diagram illustrates the stages that occur in an ovary during the course of a monthly cycle. The arrows indicate changes with time.

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  • Pentti
    What order do graafian follicle, corpus albicans, corpus luteum, and primary follicle?
    8 years ago

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