When oxyhemoglobin dissociation curves are constructed at different temperatures, the curve moves rightward as the temperature increases. The rightward shift of the curve indicates that the affinity of hemoglobin for oxygen is decreased by a rise in temperature. An increase in temperature weakens the bond between hemoglobin and oxygen and thus has the same effect as a fall in pH. At higher temperatures, therefore, more oxygen is unloaded to the tissues than would be the case if the bond strength were constant. This effect can significantly enhance the delivery of oxygen to muscles that are warmed during exercise.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.