The rate of an enzyme-catalyzed reaction depends on numerous factors, including the concentration of the enzyme and the pH and temperature of the solution. Genetic control of enzyme concentration, for example, affects the rate of progress along particular metabolic pathways and thus regulates cellular metabolism.
The activity of an enzyme, as measured by the rate at which its substrates are converted to products, is influenced by such factors as (1) the temperature and pH of the solution; (2) the concentration of cofactors and coenzymes, which are needed by many enzymes as "helpers" for their catalytic activity; (3) the concentration of enzyme and substrate molecules in the solution; and (4) the stimulatory and inhibitory effects of some products of enzyme action on the activity of the enzymes that helped to form these products.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.