Collecting Duct Effect of Antidiuretic Hormone ADH

As a result of the recycling of salt between the ascending and descending limbs and the recycling of urea between the collecting duct and the loop of Henle, the interstitial fluid is made very hypertonic. The collecting ducts must channel their fluid through this hypertonic environment in order to empty their contents of urine into the calyces. Whereas the fluid surrounding the collecting ducts in the medulla is hypertonic, the fluid that passes into the collecting ducts in the cortex is hypotonic as a result of the active extrusion of salt by the ascending limbs of the loops.

The medullary region of the collecting duct is impermeable to the high concentration of NaCl that surrounds it. The wall of the collecting duct, however, is permeable to water. Since the surrounding interstitial fluid in the renal medulla is very hypertonic because of the countercurrent multiplier system, water is drawn out of the collecting ducts by osmosis. This water does not dilute the surrounding interstitial fluid because it is transported by capillaries to the general circulation. In this way, most of the water remaining in the filtrate is returned to the vascular system (fig. 17.19).

Note that it is the osmotic gradient created by the counter-current multiplier system that provides the force for water reabsorption through the collecting ducts. The rate at which this osmotic movement occurs, however, is determined by the permeability of the collecting duct to water. This depends on the number of aquaporins (water channels) in the plasma membranes of the collecting duct epithelial cells.

Aquaporins are produced as proteins within the membranes of vesicles that bud from the Golgi apparatus (chapter 3). In the absence of stimulation, these vesicles are present in the cytoplasm of the collecting duct cells. When antidiuretic hormone (ADH) binds to its membrane receptors on the collecting duct, it acts (via cAMP as a second messenger) to stimulate the fusion of these vesicles with the cell membrane (chapter 6; see fig. 6.15). This is identical to exocytosis, except that here there is no secretion of product. The importance of this process in the collecting duct is that the water channels are incorporated into the plasma membrane when the vesicles and membrane fuse. In response to ADH, therefore, the collecting duct becomes more permeable to water. When ADH is no longer available to bind to its membrane receptors, the water channels are removed from the plasma membrane by a process of endocytosis. Endocytosis is the opposite of exocytosis;

Physiology of the Kidneys

Cortex tttt

Distal tubule

Outer medulla

Inner medulla

NaCl Q Urea Q Water

- Collecting duct

Inner medulla

NaCl Q Urea Q Water

Obligatory Water Reabsorption
Loop of Henle

■ Figure 17.18 The role of urea in urine concentration. Urea diffuses out of the inner collecting duct and contributes significantly to the concentration of the interstitial fluid in the renal medulla. The active transport of Na+ out of the thick segments of the ascending limbs also contributes to the hypertonicity of the medulla, so that water is reabsorbed by osmosis from the collecting ducts.

Table 17.2 Transport Properties of Different Segments of the Renal Tubules and the Collecting Ducts

Passive Transport

Nephron Segment Active Transport Salt Water

Urea

Proximal tubule

Na+

Cl-

Yes

Yes

Descending limb of Henle's loop

None

Maybe

Yes

No

Thin segment of ascending limb

None

NaCl

No

Yes

Thick segment of ascending limb

Na+

Cl-

No

No

Distal tubule

Na+

Cl-

No**

No

Collecting duct*

Slight Na+

No

Yes (ADH) or slight (no ADH)

Yes

*The permeability of the collecting duct to water depends on the presence of ADH. **The last part of the distal tubule, however, is permeable to water.

*The permeability of the collecting duct to water depends on the presence of ADH. **The last part of the distal tubule, however, is permeable to water.

the plasma membrane invaginates to reform vesicles that again contain the water channels. Alternating exocytosis and endocytosis in response to the presence and absence of ADH, respectively, is believed to result in the recycling of water channels within the cell.

When the concentration of ADH is increased, the collecting ducts become more permeable to water and more water is reabsorbed. A decrease in ADH, conversely, results in less reabsorption of water and thus in the excretion of a larger volume of more dilute urine (fig. 17.20). ADH is produced by neurons in the hypothalamus and is released from the posterior pituitary (chapter 11; see fig. 11.13). The secretion of ADH is stimulated when osmoreceptors in the hypothalamus respond to an increase in blood osmolality. During dehydration, therefore, when the plasma becomes more concentrated, increased secretion of ADH promotes increased permeability of the collecting ducts to water. In severe dehydration only the minimal amount of water needed to eliminate the body's wastes is excreted. This minimum, an obligatory water loss of about 400 ml per day, is limited by the

© The McGraw-Hill Companies, 2003

Chapter Seventeen

Proximal tubule

Vasa recta

Proximal tubule

Vasa recta

Collecting Tubules And Vasa Recta

1200

1400

Descending limb of loop

Ascending limb of loop

Descending limb of loop

Ascending limb of loop

Collecting duct

600 600

Outer medulla

1200

1400

— Inner medulla

■ Figure 17.19 The osmolality of different regions of the kidney. The countercurrent multiplier system in the loop of Henle and countercurrent exchange in the vasa recta help to create a hypertonic renal medulla. Under the influence of antidiuretic hormone (ADH), the collecting duct becomes more permeable to water, and thus more water is drawn out by osmosis into the hypertonic renal medulla and peritubular capillaries.

fact that urine cannot become more concentrated than the medullary tissue fluid surrounding the collecting ducts. Under these conditions about 99.8% of the initial glomerular ultrafil-trate is reabsorbed.

A person in a state of normal hydration excretes about 1.5 L of urine per day, indicating that 99.2% of the glomerular ultrafil-trate volume is reabsorbed. Notice that small changes in percent reabsorption translate into large changes in urine volume. Drinking more water—and thus decreasing ADH secretion (fig. 17.20 and table 17.3)—results in correspondingly larger volumes of urine excretion. It should be noted, however, that even in the complete absence of ADH some water is still reabsorbed through the collecting ducts.

B it Diabetes insipidus is a disease associated with the inadequate secretion or action of ADH. When the se-^ cretion of ADH is adequate, but a genetic defect in the ADH receptors or the aquaporin channels renders the kidneys incapable of responding to ADH, the condition is called nephrogenetic diabetesinsipidus. Without proper ADH secretion or action, the collecting ducts are not very permeable to water, and so a large volume (5 to 10 L per day) of dilute urine is produced. The dehydration that results causes intense thirst, but a person with this condition has difficulty drinking enough to compensate for the large volumes of water lost in the urine.

© The McGraw-Hill Companies, 2003

Physiology of the Kidneys 539

Table l7.3

Antidiuretic Hormone Secretion and Action

Stimulus

Receptors

Secretion of ADH

Effects on Urine Volume

Effects on Blood

TOsmolality (dehydration)

Osmoreceptors in hypothalamus

Increased

Decreased

Increased water retention; decreased blood osmolality

^Osmolality

Osmoreceptors in hypothalamus

Decreased

Increased

Water loss increases blood osmolality

ÎBlood volume

Stretch receptors in left atrium

Decreased

Increased

Decreased blood volume

iBlood volume

Stretch receptors in left atrium

Increased

Decreased

Increased blood volume

Low water intake (dehydration)

High water intake (over-hydration)

Low water intake (dehydration)

f Plasma osmolality-

High water intake (over-hydration)

J Plasma osmolality

Osmoreceptors in hypothalamus

Posterior pituitary fADH

Kidneys

Negative feedback correction f Water reabsorption

Less water ;reted in urir

Negative feedback correction j Water reabsorption o

More water excreted in urine

Negative feedback correction

■ Figure 17.20 Homeostasis of plasma concentration is maintained by ADH. In dehydration (left side of figure), a rise in ADH secretion results in a reduction in the excretion of water in the urine. In overhydration (right side of figure), the excess water is eliminated through a decrease in ADH secretion. These changes provide negative feedback correction, maintaining homeostasis of plasma osmolality and, indirectly, blood volume.

Test Yourself Before You Continue

1. Describe the mechanisms for salt and water reabsorption in the proximal tubule.

2. Compare the transport of Na+, Cl-, and water across the walls of the proximal tubule, ascending and descending limbs of the loop of Henle, and collecting duct.

3. Describe the interaction between the ascending and descending limbs of the loop and explain how this interaction results in a hypertonic renal medulla.

4. Explain how ADH helps the body to conserve water. How do variations in ADH secretion affect the volume and concentration of urine?

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Responses

  • toivo
    Why in the presence of adh water reabsorption is only 99.8%?
    8 years ago
  • david
    How are the walls of the loop of henle and collecting duct adapted to conserve water?
    8 years ago
  • ERIC
    How does water affect the ADH hormone?
    8 years ago
  • marmaduc
    What happened to the concentration when the collecting duct walls are permeable water?
    8 years ago
  • CATRIONA
    Which hormone impacts on colleting ducts function?
    8 years ago
  • JESSICA
    How adh conserves body water steps?
    8 years ago
  • Dawit
    What effect does adh have on the cells on the walls of the collecting duct?
    8 years ago
  • Swen
    Does adh decrese the urea permeability int he medullary collecting tubules?
    8 years ago
  • findlay
    What is the function of the collecting tubules under the influence of adh?
    8 years ago
  • taylor
    What is drawn of the collecting duct?
    8 years ago
  • BIRIKTI
    Which hormone is secreted in the collecting duct?
    8 years ago
  • adonay
    Does adh increase the permeability of the collecting ducts to water?
    8 years ago
  • caitlyn
    Why does the antidiuretic hormone acts directly on the collecting duct?
    8 years ago
  • Bucca Burrows
    How is adh released into collecting duct?
    8 years ago
  • Maxima
    What effects does the adh hormine have on the cells of the collecting ducts?
    8 years ago
  • efrem demsas
    When ADH levels are high, membranes in CD (collecting duct) are very permeable to water?
    8 years ago
  • semret
    What makes water channels appear in the descending loop and collecting duct?
    8 years ago
  • antonia
    Does antidiuretic hormone decreases the permeability of the collecting duct to urea?
    8 years ago
  • Antje
    When dehydrated is water permeability of the collecting ducts decrease?
    8 years ago
  • brian
    What is the role of a collecting duct and which hormone impacts on this?
    8 years ago
  • kati timonen
    Does antidiuretic hormone cause aquaporins to be formed in collecting ducts?
    7 years ago
  • ruben fifield
    How does blood volume effect the level of ADH in the collecting duct?
    7 years ago
  • may
    What is ascending vasa recta in kidney?
    7 years ago
  • roderick
    What are the meduallary regions of the collecting ducts permeable to?
    7 years ago
  • asmait
    How does the adh afect the collecting duct?
    7 years ago
  • Marmadoc Gammidge
    What effects does ADH have on the principal cells in the collecting ducts.?
    7 years ago
  • RHONDA HERNANDEZ
    What cells does adh binds to?
    7 years ago
  • Johanna Kunze
    When adh levels in teh blood are hight the collecting ducts are?
    7 years ago
  • martha
    What is the effect of ADH in the collecting ducts?
    7 years ago
  • eve
    What are the effects of ADH on water reabsorption at the collecting duct?
    7 years ago
  • mhret abaalom
    When ADH levels in the plasma are low, the collecting tubules are?
    7 years ago
  • melampus oldbuck
    Does blocked aquaporins in nephron increase amount of CL in collecting duct?
    7 years ago
  • saare dawit
    When ADH is secreted in greater amounts, what will happen to the fluid in the collecting ducts...?
    7 years ago
  • belladonna
    Which is an effect of antidiuertic hormone on water retention in the collecting duct?
    7 years ago
  • philipp
    How does antidiuretic hormone (ADH) affect water reabsorption in the collecting duct?
    7 years ago
  • carolyn
    How does adh affect the activity of the collecting duct?
    6 years ago
  • asphodel goodbody
    How does antidiuretic effect the collecting ducts?
    6 years ago
  • ANKE WIRTH
    Which hormone collecting duct is respond to?
    6 years ago
  • ivone
    How does ADh affect the permeability and collecting tubules?
    6 years ago
  • faruz
    What will happen to the urine volume if ADH is NOT added to the collecting duct?
    6 years ago
  • brigida trentini
    How does dehydration affect the number of aquaproins?
    6 years ago
  • Nestore
    Do adh open aquaporins in the collecting duct?
    6 years ago
  • Antje
    How ADH interacts with collecting duct?
    6 years ago
  • BARBARA
    Is the collecting duct more permeable to water or salt?
    6 years ago
  • maximilian bach
    Does ADH promotes reabsorption in collecting duct?
    6 years ago
  • linda
    How does ADH act to increase the permeability of the collecting duct to water?
    6 years ago
  • ADONAY AMANUEL
    What makes water channel apperas in the descending loopa and collecting duct?
    6 years ago
  • luca
    How does low adh effect the absorbtion of water from the collecting duct to the cappillaries?
    6 years ago
  • norman
    What effect does drinking large volumes of water have on adh secretion?
    6 years ago
  • peter
    Why does the collecting duct become insenstive to ADH?
    6 years ago
  • juliette
    What are the effects of ADH on the permeabilityof the collecting tubules?
    6 years ago
  • Jole Pagnotto
    When the cells in the collect duct are impermeable to water this results in what?
    6 years ago
  • Aleena
    What is the role of ADH and the collecting duct in a dehydrated situation?
    6 years ago
  • tommi
    Does adh make the collecting duct wall more permeable to water?
    6 years ago
  • tewolde
    What affect does oversecretion of antidiuretic hormone have on the human body?
    6 years ago
  • thomas
    How does dehydration affect water absorption at the collecting duct?
    6 years ago
  • genet
    How does adh affect the wall of the collecting ducts?
    6 years ago
  • klaudia
    How collecting duct are permeable to water in absence of ADH?
    6 years ago
  • BAILLIE
    What effect does adh have on the collecting tubule?
    6 years ago
  • Novella
    How do you think the role of Anti DiureticHormone affects fluid balance in a state ofdehydration?
    5 years ago
  • maggie
    Does dehydration increase number of aquaporins?
    5 years ago
  • Yohannes
    What does a decrease in blod osmoality mean and the collecting ducts?
    5 years ago
  • IRENEO
    What affects does ADH have on the nephron/collecting duct system?
    5 years ago
  • matthew
    How are the collecting ducts affected by the hormone ADH?
    5 years ago
  • mewael
    Does ADH increse water reabsorbtion in the collectin duct?
    5 years ago
  • gorhendad gaukrogers
    What affect does adh secretion have on the kidneys?
    5 years ago
  • karys
    How does adh influence collecting ducts?
    5 years ago
  • Ulla-Maj
    What conditions negatively affect ADH?
    5 years ago
  • yvonne
    Which hormone affects water channels in the collecting duct?
    5 years ago
  • melilot
    Are cells of collecting ducts permeable for water in the absence of adh?
    5 years ago
  • nicol zaragamba
    What effect does antidiuretic hormone (ADH) have on the nephron?
    5 years ago
  • senay
    How does adh affect the number of aquaporins?
    5 years ago
  • elena
    How ADH effects the collecting ducts premability?
    5 years ago
  • calogero
    What is the process of water concentration of the collecting duct?
    5 years ago
  • Zufan
    How does a Anti Diurectic Hormone affect fluid balance in a state of dehydration?
    5 years ago
  • pansy
    What hormone affecre the collecting duct?
    5 years ago
  • Suzanne
    Which hormone affwct permeability towater of cells if the collecting duct?
    5 years ago
  • angelica
    Does adh enhance passive movement of water out of collecting ducts?
    5 years ago
  • kenzie
    What effect does adh have on the colecting ducts?
    5 years ago
  • olavi
    What is d EFFECT of water pollect?
    5 years ago
  • olle
    Why does adh affect the walls of the collecting duct?
    5 years ago
  • Hannah
    How does antidiuretic hormone influence thje function of collecting duct?
    5 years ago
  • SARI
    Which hormone directly affects the permeability of the collecting duct to water?
    4 years ago
  • Elliott
    Which hormone inserts aquaporins into the DCT and collecting duct?
    4 years ago
  • jasmine
    What causes more aquaporins to appear in the membranes of collecting duct cells?
    4 years ago
  • caramella
    How caffeine affects the permeable of collective duct?
    4 years ago
  • Brigida Udinese
    How does ADH affect the collectinf duct?
    4 years ago
  • Lily
    What is the effect of high ADH on the late distal tubule and collecting ducts?
    4 years ago
  • david
    How many collecting ducts are in the human body?
    4 years ago
  • jarno paasilinna
    How does AHD affect the activity of the collectiing duct?
    4 years ago
  • sinit
    How does ADH affect the permeability of cell in the nephron?
    4 years ago
  • Dirk
    How does the adh affect the permeability of cells in the nephron?
    4 years ago
  • Pierino Palermo
    How is reabsorption of water in collecting duct influences high osmotic pressure in the medulla?
    4 years ago
  • sherry lieb
    Which is absorbed across the walls of the collecting duct under the influence of ADH?
    4 years ago
  • katy wood
    What makes collecting duct to respond to ADH?
    4 years ago
  • semrawit
    How does dehydration affect on permeability of collecting ducts?
    4 years ago
  • Josh
    What happens in collecting ducts when body is dehydrated and antidiuretic hormone is present?
    4 years ago
  • venanzio
    What would happen to the functioning of the collecting duct in absence of antidiuretic hormone?
    4 years ago
  • Barbara
    Do your number of aquaproins increase during dehydration?
    4 years ago
  • rollo
    How ADH conserves water in loop of henl?
    4 years ago
  • jesus
    How are the walls of the collecting duct in the kidneys made permeable?
    4 years ago
  • roma futsum
    What infulences collecting ducts?
    4 years ago
  • WERONIKA
    How does ADH affect the axtivity of the collecting duct?
    4 years ago
  • Carambo
    When ADH levels in the plasma are low, the collecting ducts are?
    4 years ago
  • melvin
    What will happen when collecting duct is removed?
    4 years ago
  • sarah
    How do variation in adh secretion affect the volume and concentration of urine?
    4 years ago
  • Cynthia Gates
    What is the effect of ADH on renals tubels?
    4 years ago
  • Rosa
    How adh cause distal tubule and collecting duct to become permeable to water?
    4 years ago
  • maxima whitfoot
    How does vasopressin effect collecting duct permeability?
    3 years ago
  • Ezio
    Does presence of antidiuretic hormone effect urine concentration and volume?
    3 years ago
  • Afwerki
    What will happen on removal of collecting ducts from kidney?
    3 years ago
  • TIZIANA
    How are the collecting ducts of kidneys affected by adh?
    3 years ago
  • Karita
    What soes ADH do to DCT collecting ducts?
    3 years ago
  • tim
    How collecting duct in the kidneys may reduce the loss of water from the body?
    3 years ago
  • Tommy Klinger
    How does ADH increase reabsorption in the collecting ducts?
    3 years ago
  • veli-pekka pietik
    How does adh affectt collecting duct'?
    3 years ago
  • suoma
    What happen when ADH is present in collectingduct?
    3 years ago
  • rudolph took-took
    What happens in the conducting duct?
    3 years ago
  • priamus
    How does hypertonic medulla of kidney increases water absorbtion?
    3 years ago
  • Bailey
    How does adh promote urine concentration?
    3 years ago
  • Temesgen
    Which hormone helps in reabsorption in collecting duct?
    3 years ago
  • jeffery
    How does adh work in the collecting duct?
    3 years ago
  • peter
    How does ADH affects the kidney tubules and their symptoms?
    3 years ago
  • andreas
    What is the effect of in urine formation when there is absence of antiduretic hormone?
    3 years ago
  • IZAAK
    Is the ADH at the outer wall of tubule or inner ?
    3 years ago
  • MARY
    What happened to the renal tubules if we increase ADH?
    3 years ago
  • bo
    How does antiduretic hormone influence the function of the collecting duct and blood pressure?
    3 years ago
  • william harper
    What is the consequences of ADH secretion on the movement of water in the nephron?
    3 years ago
  • Kelvin Stewart
    Does ADH increase or decrease permeability of collective ducts?
    3 years ago
  • zemzem
    What is the concequence of ADH secretion on the movement of water in the nephron?
    3 years ago
  • alan
    What are effects when antiduiretic hormone is absence?
    3 years ago
  • elisabetta
    Is not permeable in the presence of ADH?
    3 years ago
  • mehret
    How does antidiureticmone function?
    3 years ago
  • Chica Labingi
    How does adh affect the permiability of cells in the nephron?
    3 years ago
  • nora
    How adh affects the dct collecting fuct?
    3 years ago
  • fatima
    What are the hormone that increase or decrease yje permeabilityof both distal & collecting tubules?
    3 years ago
  • teresio trevisani
    Does ADH make the walls permeable or imperable to water?
    3 years ago
  • bertha
    How the collecting duct reduces water loss?
    3 years ago
  • kasey
    How adh influence overhydration and dehydration?
    3 years ago
  • marko
    How collecting duct conserves water?
    3 years ago
  • lexi
    What effect does ADHi n the blood have on the nephron if it is increased?
    3 years ago
  • skye
    What effect does increased ADH have on the renal tubules?
    3 years ago
  • TOGO
    What stimulates an increase in the number of aquaporin channeld in collecting duct?
    3 years ago
  • Bibiana
    How does adh help the body to conserve?
    3 years ago
  • martin
    What does adh in collecting duct stand for ?
    3 years ago
  • MACKENZIE
    Do adh always present on collecting duct?
    3 years ago
  • ernesto
    How can adh hormone can be influenced by the walls of the collecting duct?
    3 years ago
  • GABRIELLE GRANT
    What would happen if collecting duct became impermeable to urea?
    3 years ago
  • ulrich
    Which hormone does increase the permeability of DCT to water?
    3 years ago
  • Mantissa
    Which hormon does increase the permeability of D.C.T to water?
    3 years ago
  • donna
    What would happen to the process of urine formation in the absence of antidiuretic hormone?
    3 years ago
  • natalia
    What would happen to the process of urine formation in absence of antiduiretic hormone?
    3 years ago
  • Cesio
    What would happey to the function of collecting tubule in the absence of ADH?
    3 years ago
  • Jordan
    Is it active transportation in DCT while ADH in action?
    3 years ago
  • Roman
    Which hormone does increase the permiability of DCT to ewater?
    3 years ago
  • Terry
    Which hormone increase the reabsortion of water in collecting duct?
    3 years ago
  • William
    How does the permeability of the collecting ducts affect the volume of uribne?
    3 years ago
  • ferdinand
    How ADG makes collecting duct permeable?
    3 years ago
  • LIISI
    When adh binds to receptors why doesnt water enter the collecting duct?
    3 years ago
  • leslie
    What will happen when the ADH secretion is reduced?
    3 years ago
  • Gerardino
    What happens to the collecting ducts when ADH levels are high in the blood?
    3 years ago
  • Gabriele
    What are the effects of anti diuretic hormone in the body?
    3 years ago
  • fiyori muhammed
    Does antidiuretic homrone affects dct?
    2 years ago
  • Torsten Huber
    Where does ADH affects the tubule permeability?
    2 years ago
  • Marco
    Where in the nephron is adh most active?
    2 years ago
  • eija
    What would happen if a person produced less antidiuretic hormone?
    2 years ago
  • Arto
    Does Antidiuretic hormone make the collecting duct less permiable to water?
    2 years ago
  • maxima
    How does the hormone ADH change the permeability of the collecting duct?
    2 years ago
  • welde
    How does adh affect the collecting duct of a nephron?
    2 years ago
  • seredic
    Why adh is secreted low when we drink more water?
    2 years ago
  • veronica
    When ADH attaches to a receptor on a collecting duct, what happens to aquaporins?
    2 years ago
  • Ellis Baugh
    When number of aquaporins in collecting duct increase?
    2 years ago
  • NICOLAS
    How collecting ducts in the kidney may reduce water loss from the body?
    2 years ago
  • linda
    What happen to the process of urine formation in the absence of antidiuretic hormon?
    2 years ago
  • claudia
    How does ADH affect the collecting tubule wall in kidney?
    2 years ago
  • Giorgia
    How ADH affects the kidney tubels?
    2 years ago
  • Fatima
    What is the consequence of adh secretion on the movement of water in the nephron?
    2 years ago
  • william
    What is the collective name of the fluid waste product in the collecting duct?
    2 years ago
  • dennis
    How does ADH affect permeability of cells on the nephrone?
    2 years ago
  • Catriona
    What is the consequences of ADHh secrection on tge movement of water in the nephron?
    2 years ago
  • amaranth sandyman
    How adh affect the kidney tubules?
    2 years ago
  • Neave
    What is the relationship between level of ADH and tubular absorption of water?
    2 years ago
  • may
    How does ADH affect the permameability of cells in the nephron?
    2 years ago
  • Hallie
    What is the relationship between the level of ADH and tubular reabsorption of water?
    2 years ago
  • eldridge
    How does the level of ADH affect the kidney tubules?
    2 years ago
  • Anas
    Why in healthy person glucose no longer appears in collect duct of nephron?
    2 years ago
  • prisca
    What is the effect of antidiuretic hormone on the kidney nephrone?
    2 years ago
  • ralph
    How does adh act in the concentration of water in the nephron?
    2 years ago
  • Rosamunda
    What is the effect of adh on the tubular wall?
    2 years ago
  • Ulpu Reinikainen
    Which two hormon exert their effect in the nephron?
    2 years ago
  • Lorenza
    How does adh sffect the permeability of cells and the nepron?
    2 years ago
  • danny
    How collecting duct may reduce loss of wster in the body?
    2 years ago
  • Dodinas
    How ADH stimilates absorption from collecting tubules of nephrons?
    2 years ago
  • j
    What does it mean to have more aquarporins in collecting ducts?
    2 years ago
  • sabrina klein
    What are the hormones that affect the function of collecting duct,DCT?
    2 years ago
  • KARRI
    Which hormone increases permeability of the collecting duct?
    2 years ago
  • sebastian
    What does the Anti duretic hormone do to the distal convulated tubule during high water levels?
    2 years ago
  • thomas fassbinder
    How does adh increase water reabsorption?
    2 years ago
  • Daniela
    Which hormon has to control permiability for water in collectingtubule?
    2 years ago
  • hiewan
    What happens to urea when adh level increases?
    2 years ago
  • LAVINIA
    What adh increases on the wall of collecting duct ?
    2 years ago
  • milla
    How does alcohol and caffeine affect adh secretion?
    2 years ago
  • TOINI
    What is the effect of adh production on nephron?
    2 years ago
  • tewolde
    What would happen to collecting tubule in the absence of ADH?
    2 years ago
  • alfonso
    Does filtrate become concentrated in collecting duct?
    2 years ago
  • charli
    Do antidiuretic hormone enhances water retention by opening aquaporins?
    2 years ago
  • SELMA
    What will happen to collecting duct due to abscence of antiduretic hormone?
    1 year ago
  • gildo
    What will happen to the functioning of collecting duct in the absence of antiduretic hormone?
    1 year ago
  • Karen
    What can happen if the collecting ducts absorb too much water?
    1 year ago
  • peony
    How does water conservation occur at collecting ducts?
    1 year ago
  • EOGHAN
    What would happen to the functioning of portion 3 in the absence of anti diuratic hormone?
    1 year ago
  • piia-noora
    What does ADH affect in the kidney with reabsorption in the collecting duct?
    1 year ago
  • Damiano
    How do the vatiations in ADH secretion affect the volume and concentration of urine?
    1 year ago
  • may
    How does variation in ADH affect water and comcentration of urine.?
    1 year ago
  • prima
    When ADH levels in the blood are high ,the collecting jucts are?
    1 year ago
  • dorothy
    Which part of a kidney tubule does adh make more permeable?
    1 year ago
  • mebrahtu tewolde
    How does antidiuretic hormone influence colleccting duct?
    1 year ago
  • prima
    Which diagram shows the collecting tubule under the influence of a high level of adh?
    1 year ago
  • asmara
    What haplens to wall of dct when vasopressin is released?
    1 year ago
  • Amy
    What relationship exists between the level of ADH and tubular reabsorption of water?
    1 year ago
  • GOODWILL
    WHAT WILL HAPPEN TO PROCESS OF URINE FORMATION IN ABSENCE OF VASOPRESSIN HORMONE?
    1 year ago
  • Robert
    What is the consiquence of ADH secretion on the movement of water in the Nephron?
    1 year ago
  • sini keskitalo
    What relationship exists between the level of ADH and tubular re absorption of water?
    1 year ago
  • kaleb
    Why no glucose appears in collecting duct?
    1 year ago
  • Felix
    What happens to the collecting tubule when the ADH hormones are absent?
    1 year ago
  • isto per
    How does permeability of collecting duct cahnge?
    1 year ago
  • asmarina
    What happens adh bond to duct cells?
    12 months ago
  • archibald davidson
    How are vesicles formed in the walls of the collecting duct?
    10 months ago
  • daniela toscani
    Why do collecting ducts do not respond adh stimulation?
    10 months ago
  • helj
    Which part of the nephron adh binds to?
    10 months ago
  • roxanne
    What does caffeine do to the wall of the collecting duct?
    10 months ago
  • kifle
    How does the collecting duct reclaim water by adh?
    10 months ago
  • calogero
    How ADH concentrates urine within collecting ducts?
    9 months ago
  • graziella
    Does beer increase permeability of the collecting ducts of the nephrons?
    9 months ago
  • philipp
    How does ADH causes cells of the kidney to insert aquaporins?
    9 months ago
  • rosa
    What is the response of the collecting tubes after secretion?
    9 months ago
  • krystle
    How adh effects permeability of cell lining?
    9 months ago
  • Demi-leigh
    What happens in the collecting ductvwhen ADH is released?
    8 months ago
  • Rita
    What effect does adh have on collecting duct wall body temp?
    8 months ago
  • Giorgia
    How does aldosterone affect nephrons?
    7 months ago
  • arthur
    When adh level in the blood are high, the collecting ducts are:?
    7 months ago
  • bungo
    How are water and electrolytes reabsorbed in the collecting duct ADH?
    6 months ago
  • sophie
    What is the effect of antidiuretic hormone on the cells of the collecting duct?
    6 months ago
  • martti almila
    What does the collecting duct of the nephrone do?
    6 months ago
  • saba
    How ADH can change in the collecting ducts?
    6 months ago
  • Alice
    Which hormone acts on the collecting ducts in the kidney to increase water retention?
    6 months ago
  • Medardo
    How does alcohol affect the collecting duct of kdineys?
    6 months ago
  • marcus tuomisto
    What is the effect of antidiuretic hormone on the cells of the collecting ducts?
    5 months ago
  • meaza
    What part of the nephron/collecting duct system responds to the effects of ADH?
    5 months ago
  • bell
    How does adh manipulate permeability of collecting duct?
    5 months ago
  • jan
    How does hydration affect ADH and aldosterone in the nephron?
    4 months ago
  • tewelde
    Does ADH make the collecting duct walls less permeable?
    4 months ago
  • jonne
    What are the dct and collecting ducts in the kidneyadh?
    4 months ago
  • joshua
    Why do antiduiretic hormones act on the collecting duct?
    4 months ago
  • SELASSIE
    Why in a healthy person no glucose appears in the collecting duct?
    2 months ago
  • vappu
    How does adh work in the duct wall?
    2 months ago
  • Fiori
    Is glucose in the collecting ducts?
    3 days ago
  • massawa
    What impact does the presence of water channels have on permeability?
    2 days ago

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