T

T (tumor) antigens, 182 1 cell immunodeficiency, 132 T lymphocytes, classes, 122-124

in recovery from viral infection, 131-132 viral replication in, 535-536, 541-544 Tacaribe viruses, 501 Tana pox, 357

laxonomy, see Classification of viruses Teratogenic viruses, 337-338, 428-429, 586-587

Tick-borne encephalitis, 444-445 Tick-borne viruses, 251-254 bunyaviruses, 511, 518 flavivirus, 444-445 orthomyxoviruses, 491 reoviruses, 528-529 Togai'irulae, 418-432, see also Alphamnts, Rubella virus classification, 24, 418, 419 Torovnus, 452

Transcriptase, viral, 13, 36-44, see also Re verse transcriptase Transcription, viral, 41-45 regulation, 41-44

Transcription unit, 42 Transformation of cells, 75, 172-174 Transgenic mice, 66, 85, 117, 163, 181 TrnnMent aplastic crisis, 288, 290 Translation, inhibition of cellular, 75, 76, 81

viral, 45-46 Transmission of viruses, 242-244 germline, 176 horizontal, 242-244

tTansovarial, in arthropods, 253-254, 438,

514, 515, 518 trans-stadial, 254 , 518 vertical, 244, 251 Trisodium phosphoformate, .see Foscarnet Tropical spastic paresis, 537, 576 Tumor induction, by DNA viruses, 182-188 by retroviruses, 176-181 Tumor-specific transplantation antigens, 174 Tumoi suppressor genes, 172, 187

Uncoating of viruses, 36 Upper respiratory tract infection (URTI), 565 Uptake of viruses, 35-36 Urine, virus in, 101-102 arenaviruses, 504, 505 cytomegalovirus, 334 hantaviruses, 519 rubella virus, 157, 429

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